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Comparative biochemical studies on natural Trypanosoma evansi infection in she-camels

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Abstract

The biochemical changes associating Trypanosoma evansi infection in pregnant and non-pregnant camels were investigated. Based on pregnancy diagnosis and serological findings, camels were classified into four groups as non-pregnant healthy camels (N = 6), non-pregnant camels infected with T. evansi (N = 6), pregnant healthy camels (N = 6), and pregnant camels infected with Trypanosoma evansi (N = 8). The results revealed significant decreases (p < 0.05) in serum total proteins, albumin and globulins levels, and significant increases (p < 0.05) in serum total cholesterol and blood urea nitrogen (BUN) levels in pregnant camels infected with T. evansi compared with healthy pregnant camel. On the other hand, there were hyperproteinemia and hyperglobulinemia in healthy pregnant camel compared with non-pregnant camel. It could be concluded that the biochemical changes associating T. evansi infection in pregnant camels are hypoproteinemia, hypoalbuminemia, and hypoglobulinemia and increased serum total cholesterol and BUN levels.

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References

  • Black S, Vanderweed V (1989) Serum lipoproteins are required for multiplication of Trypanosoma brucei brucei under axenic culture conditions. Mol Biochem Parasitol 37:65–72

    Article  PubMed  CAS  Google Scholar 

  • Boid R, Jones TW, Luckins AG (1985) Protozoal diseases of camels. Br Vet J 141:87–105

    Article  PubMed  CAS  Google Scholar 

  • Coles EH (1986) Veterinary clinical pathology, 4th edn. Saunders Comp, Philadelphia

    Google Scholar 

  • Derakhshanfar A, Mozaffari AA, Mohaghegh Zadeh A (2010) An outbreak of Trypanosomiasis (Surra) in Camels in the Southern Fars Province of Iran: clinical, hematological and pathological findings. Res J Parasitol 5:23–26

    Article  Google Scholar 

  • Diall O, Bajyana Songa E, Magnus E, Kouyate B, Diallo B, Van Meirvenne N, Hamers R (1994) Evaluation of direct serological card agglutination test in the diagnosis of camel trypanosomosis due to Trypanosoma evansi. Rev Sci tech Off Int Epiz 13(3):793–800

    CAS  Google Scholar 

  • Egbe-Nwiyi TN, Chaudry SUR (1994) Trypanosomiasis: prevalence and pathology of camel of arid zone of north eastern Nigeria. Trop Vet 20:30–34

    Google Scholar 

  • Eltohamy MM, Salama A, Yousef AA (1986) Blood glucose in relation to the reproductive state in she-camel (Camelus dromedaries). Beitr Trop Landwirtsch Veterinärmed 24(4):425–430

    PubMed  CAS  Google Scholar 

  • Enwezor FNC, Sackey AKB (2005) Camel trypanosomosis: a review. Vet Arch 75:439–452

    Google Scholar 

  • Esievo KAN, Saror DI (1991) Immunochemistry and immunopathology of animal trypanosomiasis. Vet Bull 61:765–777

    Google Scholar 

  • Green HP, Portela MPM, St Jean EN, Lugli EB, Raper J (2003) Evidence for a Trypanosoma brucei lipoprotein scavenger receptor. J Biol Chem 278:422–427

    Article  PubMed  CAS  Google Scholar 

  • Gutierrez C, Juan A, Corbera MC, Juste DF, Morales I (2006) Clinical, hematological, and biochemical findings in an outbreak of abortion and neonatal mortality associated with Trypanosoma evansi infection in Dromedary Camels. Ann N Y Acad Sci 1081:325–327

    Article  PubMed  Google Scholar 

  • Higgins AJ (1983) Observations on the Arabian camel (Camelus dromedaries) and their control. Vet Bull 53:1089–1099

    Google Scholar 

  • Jatkar PR, Ghosal AK, Singh M (1973) Pathogenesis of anaemia in Trypanosoma evansi infection. III. Studies on serum proteins (in camel). Indian Vet J 50(7):634–636

    Google Scholar 

  • Logan-Henfrey LL, Gardiner PR, Mahmoud MM (1992) In: Kreier JP, Baker JR (eds) Parasitic protozoa, 2. Academic, San Diego, pp 157–275

    Google Scholar 

  • Murray M, Dexter TM (1988) Anaemia in bovine African trypanosomiasis. Acta Trop 45:389–432

    PubMed  CAS  Google Scholar 

  • Ngerenwa JJ, Gathumbi P, Mutiga ER, Agumba GJ (1993) Pathogenesis of Trypanosoma (brucei) evansi in small east African goats. Res Vet Sci 54:283–289

    Article  Google Scholar 

  • Nok AJ, Nock AH, Bonire JJ (2003) The cholesterol pathway of Trypanosoma congolense could be a target for triphenylsiliconsalicylate inhibition. Appl Organomet Chem 17:17–22

    Article  CAS  Google Scholar 

  • Olaho-Mukani W, Nyangao JMN, Ouma JO (1996) Comparison of suratex, parasite detection and antigen-ELISA for the evaluation of treatment efficacy and diagnosis of surra in dromedary camels. J Camel Parasitol Res 3:1–5

    Google Scholar 

  • Pacholek X, Gamatic D, Franekm SG, Tibayrene R (2001) Prevalence of Trypanosoma evansi trypanosomiasis in young camels in west Niger. Rev Élev Méd Vét Pays Trop 44:177–182

    Google Scholar 

  • Reid SA (2002) Trypanosoma evansi control and containment in Australia. Trends Parasitol 182:19–224

    Google Scholar 

  • Schwartz HJ, Dioli M (1992) The one-humped camel in Eastern Africa: a pictorial guide to diseases, health care and management. Verlag Josef Margraf, P.O. Box 105, pp 1–10

  • Woo PTK (1970) The haematocrit centrifugation technique for the diagnosis of African trypanosomiasis. Acta Trop 27:384–386

    PubMed  CAS  Google Scholar 

  • Zweygarth E, Sabwa C, Röttche D (1984) Serodiagnosis of trypanosomiasis in dromedary camels using a card agglutination test set (TESTRYP® CATT). Ann Soc Belge Méd Trop 64:309–313

    CAS  Google Scholar 

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Correspondence to Mahmoud R. Abd Ellah.

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Megahed, G.A., Abd Ellah, M.R. & Abdel-Rady, A. Comparative biochemical studies on natural Trypanosoma evansi infection in she-camels. Comp Clin Pathol 21, 1121–1124 (2012). https://doi.org/10.1007/s00580-011-1243-2

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