Abstract
The aim of this study was to determine the blood protein changes during different stages of pregnancy and to compare with prepregnancy diestrus in ewes. A total of 90 blood samples were taken from ten Makuii ewes (the native sheep breed in Iran) at diestrus and on days 8, 14, 28, 45, 60, 90, 125, and 145 of pregnancy. Serum protein electrophoresis of samples exhibited four fractions: albumin, α, β, and γ fractions in Makuii ewes, which in α- and γ-globulin bands were divided to α1 and α2; and γ1 and γ2, respectively. The mean concentrations (in gram per deciliter) of total serum proteins, albumin, α1-, α2-, β-, γ1-, and γ2-globulin at diestrus period were 7.03, 3.77, 0.18, 0.74, 0.41, 1.56, and 0.41, respectively. Those values fluctuated nonsignificantly throughout gestation until the 125th day of pregnancy. Thereafter, a significant decrease (p < 0.01) in serum protein levels occurred at the 145th day of pregnancy compared to prepregnancy and other gestational time points. It was concluded that blood protein levels declined sharply during late gestation when the nutrient demands of the fetus were maximal.
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The authors thank all the staff of the animal husbandry unit for taking care of the ewes and the sampling and Dr. Kheradmand of Lorestan University for his participation in statistical analysis.
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Batavani, R.A., Ansari, M.H. & Asri, S. Concentrations of serum total protein and protein fractions during diestrus and pregnancy in Makuii ewes. Comp Clin Pathol 15, 227–230 (2006). https://doi.org/10.1007/s00580-006-0648-9
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DOI: https://doi.org/10.1007/s00580-006-0648-9