Skip to main content
SpringerLink
Log in

Transesophageal Echocardiography is Suitable for Evaluating the Stage of Takayasu Arteritis with Aortic Aneurysm

  • Original Article
  • Published:
International Journal of Angiology

Abstract

Takayasu arteritis (TA) is occasionally complicated with aneurysm formation. Imaging modalities, such as CT and MRI, can detect aortic wall inflammatory lesions but not the stage of inflammation. Here we evaluated the usefulness of transesophageal echo (TEE) for detection of TA inflammatory lesions and their stages. Aortae were obtained from 9 autopsies of patients with TA. Specimens were evaluated while in degassing water. The distance between the specimen and TEE transducer (5.0-MHz, electric sector scanning) was constant for all specimens. The echo gain was set at 52, which visualized delineation of the normal left ventricle in degassing water. The areas observed by ultrasonography were then examined histopathologically. Eight atherosclerotic aneurysms with/without mural thrombi and 7 normal aortae were included as control samples and processed in a similar fashion. TA showed two patterns: 2 showed intima-media thickening (IMT) and dense echogenic layers outside of IMT, corresponding to the acute stage of TA, and 7 showed a single thickened echogenic homogeneous layer, corresponding to the scar stage of TA. Atherosclerotic aneurysms included 6 samples with mural thrombi and their image were echogenic and showed heterogeneous thin layers, while 2 samples had no mural thrombi and the images showed thickened inner echogenic layer combined with localized sonolucent area. Normal control aortae showed IMT. TEE is a suitable imaging modality for determining the pathology of aneurysm and stage of inflammation in Takayasu arteritis.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. T Nasu (1982) ArticleTitleTakayasu’s truncoarteritis; Pulseless disease or aortitis syndrome. Acta Pathol Jpn 32 IssueIDsuppl 1 117–131 Occurrence Handle6139930

    PubMed  Google Scholar 

  2. JH Park JW Chung JG Im SK Kim YB Park MC Han (1995) ArticleTitleTakayasu arteritis: Evaluation of mural changes in the aorta and pulmonary artery with CT angiography. Radiology 196 89–93 Occurrence Handle1:STN:280:ByqA3cvgsFA%3D Occurrence Handle7784596

    CAS  PubMed  Google Scholar 

  3. S Sharma S Sharma K Taneja AK Gupta M Rajani (1996) ArticleTitleMorphologic mural changes in the aorta revealed by CT in patients with nonspecific aortoarteritis (Takayasu arteritis). AJR 167 1321–1325 Occurrence Handle1:STN:280:ByiD28joslM%3D Occurrence Handle8911205

    CAS  PubMed  Google Scholar 

  4. G Ferretti P Defaye F Thony Y Rnchoup M Coulomb (1996) ArticleTitleIntimal isolated Takayasu arteritis of the right pulmonary artery: MR appearance. Eur Radiol 6 429–432 Occurrence Handle1:STN:280:BymA1M7gsVc%3D Occurrence Handle8798016

    CAS  PubMed  Google Scholar 

  5. K Hayashi Y Ogawa I Sakamoto Y Matsuoka N Matsunaga (1996) ArticleTitleImaging of Takayasu arteritis in the acute stage. Br J Radiol 69 189–191 Occurrence Handle1:STN:280:BymB2cnhvVU%3D Occurrence Handle8785651

    CAS  PubMed  Google Scholar 

  6. N Matsunaga K Hayashi I Sakamoto Y Matsuoka Y Ogawa K Honjo K Takano (1998) ArticleTitleTakayasu Arteritis: MR manifestations and diagnosis of acute and chronic phase. JMRI 8 406–414 Occurrence Handle1:STN:280:DyaK1c3itVGgtA%3D%3D Occurrence Handle9562068

    CAS  PubMed  Google Scholar 

  7. YH Choe BK Han EM Koh DK Kim YS Do WR Lee (2000) ArticleTitleTakayasu’s arteritis: Assessment of disease activity with contrast-enhanced MR imaging. AJR 175 505–511 Occurrence Handle1:STN:280:DC%2BD3cvgvVSksQ%3D%3D Occurrence Handle10915704

    CAS  PubMed  Google Scholar 

  8. E Tso SD Flamm RD White PR Schvartzman E Mascha GS Hoffman (2002) ArticleTitleTakayasu Arteritis: Utility and limitations of magnetic resonance imaging in diagnosis and treatment. Arthritis Rheum 46 1634–1642 Occurrence Handle10.1002/art.10251 Occurrence Handle12115196

    Article  PubMed  Google Scholar 

  9. H Maeda N Hanada M Matsumoto H Hougaku S Ogawa N Oku T Itoh H Moriwaki S Yoneda K Kimura T Kamada (1991) ArticleTitleCarotid lesions detected by B-mode ultrasonography in Takayasu arteritis: “macaroni sign” as an indicator of the disease. Ultrasound Med Biol 17 695–701 Occurrence Handle1:STN:280:By2C2c3jt1I%3D Occurrence Handle1685816

    CAS  PubMed  Google Scholar 

  10. Y Sun PK Yip JS Jeng BS Hwang WH Lin (1996) ArticleTitleUltrasonographic study and long-term follow-up of Takayasu arteritis. Stroke 27 2178–2182 Occurrence Handle1:STN:280:ByiC38vmtVI%3D Occurrence Handle8969776

    CAS  PubMed  Google Scholar 

  11. S Sharma S Sharma K Taneja VK Bahl M Rajani (1998) ArticleTitleMorphological mural changes in the aorta in non-specific aortoarteritis (Takayasu arteritis): Assessment by intravascular ultrasound imaging. Clin Radiol 53 37–43 Occurrence Handle1:STN:280:DyaK1c7isVSrsw%3D%3D Occurrence Handle9464434

    CAS  PubMed  Google Scholar 

  12. SH Park JW Chung JW Lee MH Han JH Park (2001) ArticleTitleCarotid artery involvement in Takayasu’s arteritis. J Ultrasound Med 20 371–378 Occurrence Handle1:STN:280:DC%2BD3Mvit1Krug%3D%3D Occurrence Handle11316316

    CAS  PubMed  Google Scholar 

  13. WA Schmidt A Nerenheim E Seipelt C Poehls E Gromnica-Ihle (2002) ArticleTitleDiagnosis of early Takayasu arteritis with sonography. Rheumatology 41 469–502

    Google Scholar 

  14. GS Kerr CW Hallahan J Gordano RY Leavitt AS Fauci M Rottem GS Hoffman (1994) ArticleTitleTakayasu arteritis. Ann Intern Med 120 919–929

    Google Scholar 

  15. CC Chen GS Kerr CS Carter EJ Read JA Carrasquillo SF Leitman GS Hoffman (1995) ArticleTitleLack of sensitivity of Indium-111 mixed leukocyte scans for active disease in Takayasu’s arteritis. J Rheumatol 22 478–481 Occurrence Handle1:STN:280:ByqA3c3jsFQ%3D Occurrence Handle7783065

    CAS  PubMed  Google Scholar 

  16. R Pajari P Hekali RT Harjola (1986) ArticleTitleTreatment of Takayasu arteritis: An analysis of 29 operated patients. Thorc Cardiovasc Surg 34 176–181 Occurrence Handle1:STN:280:BimB1M%2Fjt1Y%3D

    CAS  Google Scholar 

  17. S Sasaki S Kubota T Kunihara N Shiiya K Yasuda (2000) ArticleTitleSurgical experience of the thoracic aortic aneurysm due to Takayasu’s arteritis. Int J Cardiol 75 S129–S134 Occurrence Handle10.1016/S0167-5273(00)00183-2 Occurrence Handle10980351

    Article  PubMed  Google Scholar 

  18. JM Giordano (2002) ArticleTitleSurgical treatment of Takayasu’s disease. Cleve Clin J Med 69 IssueIDSuppl 2 SII146–SII148 Occurrence Handle12086255

    PubMed  Google Scholar 

  19. T Miyata O Sato J Deguchi H Kimura T Namba K Kondo M Makuuchi C Hamada A Takagi Y Tada (1998) ArticleTitleAnastomotic aneurysms after surgical treatment of Takayasu arteritis: A 40-year experience. J Vasc Surg 27 438–445 Occurrence Handle1:STN:280:DyaK1c3gs1ejtg%3D%3D Occurrence Handle9546229

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Cardiovascular Medicine, Matsuyama Shimin Hospital, Ehime, Japan

    Yoichi Nakamura M.D., Hiroshi Matsuo M.D., Ph.D., Hiroshi Sato F.I.C.A., Chikao Yutani M.D., Ph.D. & Tohru Ohe M.D., Ph.D.

Authors
  1. Yoichi Nakamura M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hiroshi Matsuo M.D., Ph.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hiroshi Sato F.I.C.A.
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Chikao Yutani M.D., Ph.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Tohru Ohe M.D., Ph.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yoichi Nakamura M.D..

About this article

Cite this article

Nakamura, Y., Matsuo, H., Sato, H. et al. Transesophageal Echocardiography is Suitable for Evaluating the Stage of Takayasu Arteritis with Aortic Aneurysm . International Journal of Angiology 12, 243–247 (2003). https://doi.org/10.1007/s00547-004-0999-5

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00547-004-0999-5

Keywords

Search

Navigation