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Design optimization of micromixer with square-wave microchannel on compact disk microfluidic platform

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Abstract

This paper presents a passive micromixer on a compact disk (CD) microfluidic platform that performs plasma mixing function. The driving force of CD microfluidic platform including, the centrifugal force due to the system rotation, the Coriolis force as a function of the rotation angular frequency and velocity of liquid. Numerical simulations are performed to investigate the flow characteristics and mixing performance of three CD microfluidic mixers with square-wave, curved and zig-zag microchannels, respectively. Of the three microchannels, the square-wave microchannel is found to yield the best mixing performance, and is therefore selected for design optimization. Four CD microfluidic micromixers incorporating square-wave PDMS microchannels with different widths in the x- and y-directions are fabricated using conventional photolithography techniques. The mixing performance of the four microchannels is investigated both numerically and experimentally. The results show that given an appropriate specification of the microchannel geometry and a CD rotation speed of 2,000 rpm, a mixing efficiency of more than 93 % can be obtained within 5 s.

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Acknowledgments

The authors gratefully acknowledge the financial support provided to this study by the National Science Council of Taiwan under Grant No. NSC 101-2221-E-150-036. In addition, the access provided to fabrication equipment by the Common Lab for Micro/Nano Science and Technology of National Formosa University is greatly appreciated.

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Authors and Affiliations

  1. Department of Automation Engineering, National Formosa University, Yunlin, 632, Taiwan

    Ju-Nan Kuo & Li-Ren Jiang

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  1. Ju-Nan Kuo
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  2. Li-Ren Jiang
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Correspondence to Ju-Nan Kuo.

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Kuo, JN., Jiang, LR. Design optimization of micromixer with square-wave microchannel on compact disk microfluidic platform. Microsyst Technol 20, 91–99 (2014). https://doi.org/10.1007/s00542-013-1769-0

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  • DOI: https://doi.org/10.1007/s00542-013-1769-0

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