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Cardiac arrest after spinal anesthesia in a patient with neurally mediated syncope

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Abstract

We present the case of cardiac arrest in a patient with neurally mediated syncope (NMS). A 66-year-old male patient was scheduled to undergo right inguinal hernioplasty. He had a history of syncope, which occurred a few times a year in childhood and once a year recently. One minute after the second spinal injection, cardiac arrest (asystole) developed. Sinus rhythm was restored by cardiac massage and intravenous administration of atropine and ephedrine. The operation was cancelled. The patient was diagnosed as NMS by a cardiologist. Four months later, right inguinal hernioplasty was performed, uneventfully, under general anesthesia. High sympathetic blockade due to spinal anesthesia and transient withdrawal of sympathetic tone and increase in vagal discharge due to NMS could be the main causes of the cardiac arrest. If the patient has any possibility of NMS, anesthesiologists should consider the possibility of cardiac arrest after spinal anesthesia.

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References

  1. Zaqqa M, Massumi A. Neurally mediated syncope. Tex Heart Inst J. 2000;27:268–72.

    CAS  PubMed  PubMed Central  Google Scholar 

  2. McConachie I. Vasovagal asystole during spinal anaesthesia. Anaesthesia. 1991;46:281–2.

    Article  CAS  PubMed  Google Scholar 

  3. Molnar J, Somberg JC. Neurocardiogenic syncope. Cardiology. 2009;114:47–9.

    Article  PubMed  Google Scholar 

  4. Pollard JB. Cardiac arrest during spinal anesthesia: common mechanisms and strategies for prevention. Anesth Analg. 2001;92:252–6.

    Article  CAS  PubMed  Google Scholar 

  5. Guise PA. Asystole following propofol and fentanyl in an anxious patient. Anaesth Intensive Care. 1991;19:116–8.

    CAS  PubMed  Google Scholar 

  6. Ebert TJ. Sympathetic and hemodynamic effects of moderate and deep sedation with propofol in humans. Anesthesiology. 2005;103:20–4.

    Article  CAS  PubMed  Google Scholar 

  7. Fukuda K. Intravenous opioid anesthetics. In: Miller RD, editor. Miller’s anesthesia. 6 ed. Philadelphia: Churchill Livingstone; 2005. p. 379–437

  8. Yamazaki M, Stekiel TA, Bosnjak ZJ, Kampine JP, Stekiel WJ. Effects of volatile anesthetic agents on in situ vascular smooth muscle transmembrane potential in resistance- and capacitance-regulating blood vessels. Anesthesiology. 1998;88:1085–95.

    Article  CAS  PubMed  Google Scholar 

  9. Picker O, Scheeren TW, Arndt JO. Inhalation anaesthetics increase heart rate by decreasing cardiac vagal activity in dogs. Br J Anaesth. 2001;87:748–54.

    Article  CAS  PubMed  Google Scholar 

  10. Connolly SJ, Sheldon R, Thorpe KE, Roberts RS, Ellenbogen KA, Wilkoff BL, Morillo C, Gent M, Investigators VI. Pacemaker therapy for prevention of syncope in patients with recurrent severe vasovagal syncope: Second Vasovagal Pacemaker Study (VPS II): a randomized trial. JAMA. 2003;289:2224–9.

    Article  PubMed  Google Scholar 

  11. Brignole M, Sutton R. Pacing for neurally mediated syncope: is placebo powerless? Europace. 2007;9:31–3.

    Article  CAS  PubMed  Google Scholar 

  12. Alboni P, Brignole M, Degli Uberti EC. Is vasovagal syncope a disease? Europace. 2007;9:83–7.

    Article  PubMed  Google Scholar 

Download references

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Correspondence to Tadahiko Ishiyama.

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Ishiyama, T., Shibuya, K., Terada, Y. et al. Cardiac arrest after spinal anesthesia in a patient with neurally mediated syncope. J Anesth 26, 103–106 (2012). https://doi.org/10.1007/s00540-011-1264-7

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  • DOI: https://doi.org/10.1007/s00540-011-1264-7

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