Abstract:
We report our experience of the surgical treatment of intrahepatic cholangiocarcinoma (ICC) in Taiwanese patients. A tota1 of 162 patients with histologically proven ICC were treated of whom 106 (65.4%) had associated hepatolithiasis. Patients with hepatolithiasis were in earlier stages than those without hepatolithiasis. Two-thirds of the patients with hepatolithiasis presented with acute cholangitis, and two-thirds of those without hepatolithiasis presented with hepatomegaly. The rate of hepatic resection was 29.6% (48 of 162), and these rates were 31.1% and 26.8% for the patients with and without hepatolithiasis, respectively. Ninety-three percent of the patients with hepatolithiasis underwent common bile duct exploration, compared with 18% of those without hepatolithiasis. The surgical mortality rates were 3.7% (6/162), for all patients, and 3.8% and 3.6% for patients with and without hepatolithiasis, respectively. The morbidity rate was much higher in the patients with hepatolithiasis (37.7% vs 16.1%). The 1-, 3-, and 5-year survival rates were 35.5%, 20.5%, and 16.5% in the patients with hepatolithiasis and 27.2%, 8.8%, and 7.8% in those without hepatolithiasis. Concomitant hepatolithiasis prevented precise diagnosis preoperatively and precipitated biliary sepsis, which affected resectability and increased postoperative morbidity. Hepatolithiasis per se did not influence long-term survival.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received for publication on Dec. 14, 1998; accepted on Dec. 15, 1998
About this article
Cite this article
Chen, MF., Jan, YY., Jeng, LB. et al. Intrahepatic cholangiocarcinoma in Taiwan. J Hep Bil Pancr Surg 6, 136–141 (1999). https://doi.org/10.1007/s005340050096
Issue Date:
DOI: https://doi.org/10.1007/s005340050096