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Evaluation of compliance with the Tokyo Guidelines for the management of acute cholangitis based on the Japanese administrative database associated with the Diagnosis Procedure Combination system

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Journal of Hepato-Biliary-Pancreatic Sciences

Abstract

Background/purpose

We aimed to evaluate compliance with the clinical practice guidelines for acute cholangitis (Tokyo Guidelines) using the Japanese administrative database associated with the Diagnosis Procedure Combination (DPC) system.

Methods

We collected database data from 60,842 acute cholangitis patients, examining 10 recommendations in the Tokyo Guidelines. We counted how many recommendations had been complied with for every patient. The patient compliance score was defined as the rate of compliance with these recommendations (score 0 = 0% to score 10 = 100%). An aggregated patient compliance score was measured according to the severity of acute cholangitis. Severity was categorized as grade I (mild cholangitis; n = 49,630), grade II (moderate cholangitis; n = 10,444), and grade III (severe cholangitis; n = 768).

Results

The mean patient compliance score was significantly higher for patients with grade III than for those with grades II and I (7.6 ± 2.1 vs. 6.5 ± 3.0 vs. 2.9 ± 0.9, p < 0.001, respectively). Multiple linear regression analysis revealed that the severity of acute cholangitis was the parameter most significantly associated with the patient compliance score. The standardized coefficient of grade III was higher than that of grade II (0.657 vs. 0.248, p < 0.001).

Conclusions

Compliance with the Tokyo Guidelines became higher in accordance with the severity of acute cholangitis.

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References

  1. Lipsett PA, Pitt HA. Acute cholangitis. Front Biosci. 2003;8:1229–39.

    Article  Google Scholar 

  2. Lum DF, Leung JW. Bacterial cholangitis. Curr Treat Options Gastroenterol. 2001;4:139–46.

    Article  PubMed  Google Scholar 

  3. Bornman PC, van Beljon JI, Krige JE. Management of cholangitis. J Hepatobiliary Pancreat Surg. 2003;10:406–14.

    Article  PubMed  Google Scholar 

  4. Takada T, Yasuda H, Hanyu F. Technique and management of percutaneous transhepatic cholangial drainage for treating an obstructive jaundice. Hepatogastroenterology. 1995;42:317–22.

    CAS  PubMed  Google Scholar 

  5. Murata A, Motomura Y, Akahoshi K, Ouchi J, Matsui N, Sumida Y, et al. Therapeutic ERCP for choledocholithiasis in patients 80 years of age and older. J Clin Gastroenterol. 2009;43:289–90.

    Article  PubMed  Google Scholar 

  6. Takada T, Kawarada Y, Nimura Y, Yoshida M, Mayumi T, Sekimoto M, et al. Background: Tokyo Guidelines for the management of acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Surg. 2007;14:1–10.

    Article  PubMed  Google Scholar 

  7. Sekimoto M, Takada T, Kawarada Y, Nimura Y, Yoshida M, Mayumi T, et al. Need for criteria for the diagnosis and severity assessment of acute cholangitis and cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:11–4.

    Article  PubMed  Google Scholar 

  8. Kimura Y, Takada T, Kawarada Y, Nimura Y, Hirata K, Sekimoto M, et al. Definitions, pathophysiology, and epidemiology of acute cholangitis and cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:15–26.

    Article  PubMed  Google Scholar 

  9. Miura F, Takada T, Kawarada Y, Nimura Y, Wada K, Hirota M, et al. Flowcharts for the diagnosis and treatment of acute cholangitis and cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:27–34.

    Article  PubMed  Google Scholar 

  10. Tsuyuguchi T, Takada T, Kawarada Y, Nimura Y, Wada K, Nagino M, et al. Techniques of biliary drainage for acute cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:35–45.

    Article  PubMed  Google Scholar 

  11. Wada K, Takada T, Kawarada Y, Nimura Y, Miura F, Yoshida M, et al. Diagnostic criteria and severity assessment of acute cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:52–8.

    Article  PubMed  Google Scholar 

  12. Tanaka A, Takada T, Kawarada Y, Nimura Y, Yoshida M, Miura F, et al. Antimicrobial therapy for acute cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:59–67.

    Article  PubMed  Google Scholar 

  13. Nagino M, Takada T, Kawarada Y, Nimura Y, Yamashita Y, Tsuyuguchi T, et al. Methods and timing of biliary drainage for acute cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:68–77.

    Article  PubMed  Google Scholar 

  14. Yasuda H, Takada T, Kawarada Y, Nimura Y, Hirata K, Kimura Y, et al. Unusual cases of acute cholecystitis and cholangitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:98–113.

    Article  PubMed  Google Scholar 

  15. Mayumi T, Takada T, Kawarada Y, Nimura Y, Yoshida M, Sekimoto M, et al. Results of the Tokyo Consensus Meeting Tokyo Guidelines. J Hepatobiliary Pancreat Surg. 2007;14:114–21.

    Article  PubMed  Google Scholar 

  16. Kuwabara K, Matsuda S, Imanaka Y, Fushimi K, Hashimoto H, Ishikawa K. The effect of age and procedure on resource use for patients with cerebrovascular disease. J Health Serv Res Policy. 2008;13:26–32.

    Article  PubMed  Google Scholar 

  17. Kuwabara K, Imanaka Y, Matsuda S, Fushimi K, Hashimoto H, Ishikawa KB, et al. Impact of age and procedure on resource use for patients with ischemic heart disease. Health Policy. 2008;85:196–206.

    Article  PubMed  Google Scholar 

  18. Kuwabara K, Matsuda S, Fushimi K, Ishikawa KB, Horiguchi H, Fujimori K. Impact of hospital case volume on the quality of laparoscopic colectomy in Japan. J Gastrointest Surg. 2009;13:19–26.

    Article  Google Scholar 

  19. Sorror ML, Maris MB, Storb R, Baron F, Sandmaier BM, Maloney DG, et al. Hematopoietic cell transplantation (HCT)-specific comorbidity index: a new tool for risk assessment before allogeneic HCT. Blood. 2005;106:2912–9.

    Article  CAS  PubMed  Google Scholar 

  20. Hui CK, Lai KC, Wong WM, Yuen MF, Lam SK, Lai CL. A randomised controlled trial of endoscopic sphincterotomy in acute cholangitis without common bile duct stones. Gut. 2002;51:245–7.

    Article  PubMed  Google Scholar 

  21. Gouma DJ. Management of acute cholangitis. Dig Dis. 2003;21:25–9.

    Article  PubMed  Google Scholar 

  22. Zhang WZ, Chen YS, Wang JW, Chen XR. Early diagnosis and treatment of severe acute cholangitis. World J Gastroenterol. 2002;8:150–2.

    PubMed  Google Scholar 

  23. Lau H, Lo CY, Patil NG, Yuen WK. Early versus delayed-interval laparoscopic cholecystectomy for acute cholecystitis. Surg Endosc. 2006;20:82–7.

    Article  CAS  PubMed  Google Scholar 

  24. Bani Hani MN. Laparoscopic surgery for symptomatic cholelithiasis during pregnancy. Surg Laparosc Endosc Percutan Tech. 2007;17:482–6.

    Article  PubMed  Google Scholar 

  25. Chang WT, Yu FJ, Hsieh MY, Huang MC, Lee KT, Chen JS, et al. Laparoscopic cholecystectomy in aged patients. Hepatogastroenterology. 2009;56:950–5.

    PubMed  Google Scholar 

  26. Giger UF, Michel JM, Opitz I, Th Inderbitzin D, Kocher T, Krähenbühl L. Risk factors for perioperative complications in patients undergoing laparoscopic cholecystectomy: analysis of 22, 953 consecutive cases from the Swiss Association of Laparoscopic and Thoracoscopic Surgery database. J Am Coll Surg. 2006;203:723–8.

    Article  PubMed  Google Scholar 

  27. Matsuda S. Casemix as a tool for transparency of medical services. Jpn J Soc Security Policy. 2008;6:43–53.

    Google Scholar 

  28. Matsuda S, Ishikawa KB, Kuwabara K, Fujimori K, Fushimi K, Hashimoto H. Development and use of the Japanese case-mix system. Eurohealth. 2008;14:25–30.

    Google Scholar 

Download references

Acknowledgments

This study was funded by Grants-in-Aid for Research on Policy Planning and Evaluation from the Ministry of Health, Labour and Welfare, Japan.

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Correspondence to Atsuhiko Murata.

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Murata, A., Matsuda, S., Kuwabara, K. et al. Evaluation of compliance with the Tokyo Guidelines for the management of acute cholangitis based on the Japanese administrative database associated with the Diagnosis Procedure Combination system. J Hepatobiliary Pancreat Sci 18, 53–59 (2011). https://doi.org/10.1007/s00534-010-0302-4

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  • DOI: https://doi.org/10.1007/s00534-010-0302-4

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