Abstract
Extensive hepatic resection is often associated with post-hepatectomy liver failure. Owing to the regenerative capacity of the liver, preoperative portal vein embolization (PVE) has been proposed to increase the functional mass of the non-embolized liver segments that will remain in situ after surgery. However, in some patients, hypertrophy of the non-embolized liver segments following PVE is insufficient to support major hepatectomy. Several studies have demonstrated alternative techniques for inducing hypertrophy of the non-embolized liver segments, including PVE in conjunction with hepatic arterial embolization or hepatic vein embolization in conjunction with PVE. Investigation of new techniques for inducing hypertrophy of the future liver remnant can reasonably be expected to expand the selection criteria for extensive hepatic resection.
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References
Kubota K, Makuuchi M, Kusaka K, Kobayashi T, Miki K, Hasegawa K, et al. Measurement of liver volume and hepatic functional reserve as a guide to decision-making in resectional surgery for hepatic tumors. Hepatology. 1997;26:1176–81.
Di Stefano DR, de Baere T, Denys A, Hakime A, Gorin G, Gillet M, et al. Preoperative percutaneous portal vein embolization: evaluation of adverse events in 188 patients. Radiology. 2005;234:625–30.
Cotroneo AR, Innocenti P, Marano G, Legnini M, Iezzi R. Pre-hepatectomy portal vein embolization: single center experience. Eur J Surg Oncol. 2009;35:71–8.
Gruttadauria S, Luca A, Mandala’ L, Miraglia R, Gridelli B. Sequential preoperative ipsilateral portal and arterial embolization in patients with colorectal liver metastases. World J Surg. 2006;30:576–8.
Nagino M, Kanai M, Morioka A, Yamamoto H, Kawabata Y, Hayakawa N, et al. Portal and arterial embolization before extensive liver resection in patients with markedly poor functional reserve. J Vasc Interv Radiol. 2000;11:1063–8.
Hiraki T, Kanazawa S. Hepatic outflow obstruction created by balloon occlusion of the hepatic vein: induced hepatic hemodynamic changes and the therapeutic applications of hepatic venous occlusion with a balloon catheter in interventional radiology. Acta Med Okayama. 2005;59:171–8.
Lee W, Chung JW, Kim HB, Kim SH, Lee JW, Han JK, et al. Acute hepatic vein occlusion: spiral CT findings in an experimental study. Abdom Imaging. 2002;27:527–35.
Murata S, Itai Y, Asato M, Kobayashi H, Nakajima K, Eguchi N, et al. Effect of temporary occlusion of the hepatic vein on dual blood in the liver: evaluation with spiral CT. Radiology. 1995;197:351–6.
Hwang S, Lee SG, Ko GY, Kim BS, Sung KB, Kim MH, et al. Sequential preoperative ipsilateral hepatic vein embolization after portal vein embolization to induce further liver regeneration in patients with hepatobiliary malignancy. Ann Surg. 2009;249:608–16.
Nagino M, Yamada T, Kamiya J, Uesaka K, Arai T, Nimura Y. Left hepatic trisegmentectomy with right hepatic vein resection after right hepatic vein embolization. Surgery. 2003;133:580–2.
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Ko, GY., Hwang, S., Sung, KB. et al. Interventional oncology: new options for interstitial treatments and intravascular approaches. J Hepatobiliary Pancreat Sci 17, 410–412 (2010). https://doi.org/10.1007/s00534-009-0235-y
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DOI: https://doi.org/10.1007/s00534-009-0235-y