Skip to main content
Log in

Safety of combined resection of the middle hepatic artery in right hemihepatectomy for hilar biliary malignancy

  • Original article
  • Published:
Journal of Hepato-Biliary-Pancreatic Surgery

Abstract

Background/purpose

In patients with hilar biliary malignancies, preservation of the middle hepatic artery (MHA, segment IV artery) where it runs close to the tumor in the hepatic hilum may lead to resection with positive margins. This retrospective study assessed the safety of combined resection of the MHA with right hemihepatectomy, caudate lobectomy, and bile duct resection for hilar biliary malignancies.

Methods

Of 61 patients with hilar biliary malignancies who underwent right hemihepatectomy, we classified the branching patterns of the MHA according to the origins and courses in the hilum. The MHA was resected without reconstruction in 16 patients in whom the artery ran close to the tumor. We compared the perioperative outcomes in these patients with those of patients who did not undergo resection of the artery.

Results

Anatomically, the MHA ran on the right side of the umbilical portion of the portal vein in 40 (66%) patients. Perioperative data for the patients who underwent combined resection were similar to those in whom the MAH was preserved. There were no postoperative complications that could be directly related to the arterial resection.

Conclusions

Combined resection of the MHA during right hemihepatectomy for hilar biliary malignancies has a safe perioperative course.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Yamaguchi R, Nagino M, Oda K, Kamiya J, Uesaka K, Nimura Y. Perineural invasion has a negative impact on survival of patients with gallbladder carcinoma. Br J Surg. 2002;89:1130–6.

    Article  CAS  PubMed  Google Scholar 

  2. Kondo S, Hirano S, Ambo Y, Tanaka E, Okushiba S, Morikawa T, et al. Forty consecutive resections of hilar cholangiocarcinoma with no postoperative mortality and no positive ductal margins: results of a prospective study. Ann Surg. 2004;240:95–101.

    Article  PubMed  Google Scholar 

  3. Skandalakis JE, Skandalakis LJ, Skandalakis PN, Mirilas P. Hepatic surgical anatomy. Surg Clin North Am. 2004;84:413–35.

    Article  PubMed  Google Scholar 

  4. Onishi H, Kawarada Y, Das BC, Nakano K, Gadzijev EM, Ravnik D, et al. Surgical anatomy of the medial segment (S4) of the liver with special reference to bile ducts and vessels. Hepatogastroenterology. 2000;47:143–50.

    CAS  PubMed  Google Scholar 

  5. Majno PE, Prêtre R, Mentha G, Morel P. Operative injury to the hepatic artery. Consequences of a biliary-enteric anastomosis and principles for rational management. Arch Surg. 1996;131:211–5.

    CAS  PubMed  Google Scholar 

  6. Gupta N, Solomon H, Fairchild R, Kaminski DL. Management and outcome of patients with combined bile duct and hepatic artery injuries. Arch Surg. 1998;133:176–81.

    Article  CAS  PubMed  Google Scholar 

  7. Tanaka K, Nishimura A, Hombo K, Furoi A, Ikoma A, Yamauchi T, et al. The development of a pyogenic liver abscess following radical resection of cholangiocellular carcinoma with ligation of the right hepatic artery: report of a case. Surg Today. 1994;24:659–62.

    Article  CAS  PubMed  Google Scholar 

  8. Smith GS, Birnbaum BA, Jacobs JE. Hepatic infarction secondary to arterial insufficiency in native livers: CT findings in 10 patients. Radiology. 1998;208:223–9.

    CAS  PubMed  Google Scholar 

  9. Ikegami T, Kawasaki S, Matsunami H, Hashikura Y, Nakazawa Y, Miyagawa S, et al. Should all hepatic arterial branches be reconstructed in living-related liver transplantation? Surgery. 1996;119:431–6.

    Article  CAS  PubMed  Google Scholar 

  10. Kondo S, Katoh H, Hirano S, Ambo Y, Tanaka E, Okushiba S. Portal vein resection and reconstruction prior to hepatic dissection during right hepatectomy and caudate lobectomy for hepatobiliary cancer. Br J Surg. 2003;90:694–7.

    Article  CAS  PubMed  Google Scholar 

  11. Mays ET, Wheeler CS. Demonstration of collateral arterial flow after interruption of hepatic arteries in man. N Engl J Med. 1974;290:993–6.

    Article  CAS  PubMed  Google Scholar 

  12. Parks RW, Chrysos E, Diamond T. Management of liver trauma. Br J Surg. 1999;86:1121–35.

    Article  CAS  PubMed  Google Scholar 

  13. Miyazaki M, Ito H, Nakagawa K, Ambiru S, Shimizu H, Yoshidome H, et al. Unilateral hepatic artery reconstruction is unnecessary in biliary tract carcinomas involving lobar hepatic artery: implications of interlobar hepatic artery and its preservation. Hepatogastroenterology. 2000;47:1526–30.

    CAS  PubMed  Google Scholar 

  14. Stratta RJ, Wood RP, Langnas AN, Hollins RR, Bruder KJ, Donovan JP, et al. Diagnosis and treatment of biliary tract complications after orthotopic liver transplantation. Surgery. 1989;106:675–83.

    CAS  PubMed  Google Scholar 

  15. Colonna JO 2nd, Shaked A, Gomes AS, Colquhoun SD, Jurim O, McDiarmid SV, et al. Biliary strictures complicating liver transplantation. Incidence, pathogenesis, management, and outcome. Ann Surg. 1992;216:344–50.

    Article  PubMed  Google Scholar 

  16. Buis CI, Hoekstra H, Verdonk RC, Porte RJ. Causes and consequences of ischemic-type biliary lesions after liver transplantation. J Hepatobiliary Pancreat Surg. 2006;13:517–24.

    Article  PubMed  Google Scholar 

  17. Nakanuma Y, Hoso M, Sanzen T, Sasaki M. Microstructure and development of the normal and pathologic biliary tract in humans, including blood supply. Microsc Res Tech. 1997;38:552–70.

    Article  CAS  PubMed  Google Scholar 

  18. Kawarada Y, Das BC, Taoka H. Anatomy of the hepatic hilar area: the plate system. J Hepatobiliary Pancreat Surg. 2000;7:580–6.

    Article  CAS  PubMed  Google Scholar 

  19. Arnold MM, Kreel L, Lo YF, Law H. Are the hepatic arteries “end arteries”? Invest Radiol. 1991;26:337–42.

    Article  CAS  PubMed  Google Scholar 

  20. Terada T, Ishida F, Nakanuma Y. Vascular plexus around intrahepatic bile ducts in normal livers and portal hypertension. J Hepatol. 1989;8:139–49.

    Article  CAS  PubMed  Google Scholar 

  21. Kondo S, Hirano S, Ambo Y, Tanaka E, Kubota T, Katoh H. Arterioportal shunting as an alternative to microvascular reconstruction after hepatic artery resection. Br J Surg. 2004;91:248–51.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Satoshi Hirano.

About this article

Cite this article

Hirano, S., Kondo, S., Tanaka, E. et al. Safety of combined resection of the middle hepatic artery in right hemihepatectomy for hilar biliary malignancy. J Hepatobiliary Pancreat Surg 16, 796–801 (2009). https://doi.org/10.1007/s00534-009-0107-5

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00534-009-0107-5

Keywords

Navigation