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Clinical significance of drainage tube insertion in laparoscopic cholecystectomy: a prospective randomized controlled trial

  • Original articles
  • Published:
Journal of Hepato-Biliary-Pancreatic Surgery

Abstract

Background/Purpose

We aimed to investigate the appropriateness of inserting an intraperitoneal drainage tube after laparoscopic cholecystectomy (LC), based on postoperative pain and clinical courses, in a randomized comparative study.

Methods

One hundred and twenty patients who were to have LC were enrolled in this prospective randomized study. An 8-mm Penrose drain was retained below the liver bed for 42 h in each of 60 patients (group A), and no drain was retained in the remaining 60 patients (group B). Patients in each group were hospitalized for 4 days after operation, and the pain reported by the patients, using a visual analogue pain scale (VAS), and the time courses of changes in the highest body temperature, leukocyte count, and C-reactive protein (CRP) were studied comparatively for men and women.

Results

Mean VAS scores were significantly greater in group A than in group B at 24 h (P = 0.00004), and 48 h (P = 0.0014) after operation. When sex-stratified changes in mean VAS scores were compared within group A, females had more pain than their male counterparts at 24 h (P = 0.030), but group B showed no sex differences. When the number of patients who used analgesics postoperatively was compared between groups A and B, analgesics were used more frequently in group A. When changes in maximum body temperature were compared, the change was significantly higher in group A than in group B on day 2 after the operation (P = 0.017).

Conclusions

Postoperative pain was intensified by the insertion of a drainage tube after LC. This tendency was stronger in women.

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Authors and Affiliations

  1. Second Department of Surgery, Wakayama Medical University, School of Medicine, 811-1 Kimiidera, Wakayama, 641-8510, Japan

    Kazuhisa Uchiyama, Masaji Tani, Manabu Kawai, Hiroshi Terasawa, Takashi Hama & Hiroki Yamaue

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  1. Kazuhisa Uchiyama
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  2. Masaji Tani
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  3. Manabu Kawai
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  4. Hiroshi Terasawa
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  5. Takashi Hama
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  6. Hiroki Yamaue
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Uchiyama, K., Tani, M., Kawai, M. et al. Clinical significance of drainage tube insertion in laparoscopic cholecystectomy: a prospective randomized controlled trial. J Hepatobiliary Pancreat Surg 14, 551–556 (2007). https://doi.org/10.1007/s00534-007-1221-x

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  • DOI: https://doi.org/10.1007/s00534-007-1221-x

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