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Does grip strength decrease in the very early stages of hematological treatment?

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Abstract

Muscle weakness in hematological cancer patients undergoing acute stages of treatment is an important concern and strong predictor of poor outcomes. However, evidence of strength loss in the very early stages of cancer treatment is not addressed. Here, we found that grip strength was compromised within the first 7 days of hematological treatment (− 2.3 kg, P = 0.002). These findings are novel in elucidating lower handgrip strength in the first week of hematological treatment and encourage additional research focusing on handgrip strength in oncology patients under initial high-dose chemotherapy routine.

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Authors and Affiliations

  1. Program of Molecular Carcinogenesis, Brazilian National Cancer Institute, Andre Cavalcanti Av. 37, Rio de Janeiro, 20231-050, Brazil

    C. G. C. Teodozio & F. T. Frajacomo

  2. Department of Nutrition and Dietetics, Brazilian National Cancer Institute, Rio de Janeiro, Brazil

    G. V. Chaves

  3. Division of hematology, Brazilian National Cancer Institute, Rio de Janeiro, Brazil

    I. P. Arcuri

Authors
  1. C. G. C. Teodozio
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  2. G. V. Chaves
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  3. I. P. Arcuri
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  4. F. T. Frajacomo
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Corresponding author

Correspondence to F. T. Frajacomo.

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The study was approved by the local Human Research Ethics committee (#1.576.178) and all patients obtained informed written consent.

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The authors declare that they have no conflict of interest.

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Teodozio, C.G.C., Chaves, G.V., Arcuri, I.P. et al. Does grip strength decrease in the very early stages of hematological treatment?. Support Care Cancer 26, 333–335 (2018). https://doi.org/10.1007/s00520-017-3932-0

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  • DOI: https://doi.org/10.1007/s00520-017-3932-0

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