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Sport bei Migräne

Übersicht und Diskussion sowie Implikationen für zukünftige Studien

Exercise in migraine treatment

Review and discussion of clinical trials and implications for further trials

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Zusammenfassung

Regelmäßiger Ausdauersport findet sich in vielen allgemeinen Empfehlungen zur Behandlung von Migränepatienten. Die Datenlage, auf der diese Empfehlungen beruhen, ist jedoch schwach, überwiegend genügen die Studien nicht modernen Ansprüchen. Häufig ist die Diagnose einer Migräne nicht überzeugend, die Behandlungszeit zu kurz, die durchgeführte Intervention nicht streng definiert und auch die Therapiekontrolle mangelhaft. Die Studien widersprechen sich darüber hinaus bzgl. ihres Effekts auf den Kopfschmerzverlauf. Regelmäßiger Ausdauersport könnte unspezifisch über Verbesserung der Fitness, jedoch auch über Mechanismen wirken, wie sie bei der regelmäßigen Anwendung von Entspannungsverfahren postuliert werden. Unklar ist weiterhin, ob Ausdauersport nur als Teil eines eher multidimensionalen Therapieansatzes oder auch alleine wirksam ist. Theoretische Überlegungen und die vorliegenden Studien und Fallserien lassen eine Wirksamkeit von regelmäßigem Ausdauersport zwar vermuten, nach aktuellen Evidenzkriterien ist dies jedoch nicht belegt. Künftige Studien müssen sich hier an der Qualität der randomisierten klinischen Studien zur medikamentösen Migräneprophylaxe orientieren.

Abstract

Regular exercise is recommended in general treatment guidelines for migraine. However, scientific evidence in support of this recommendation is weak. The majority of available trials on this topic do not meet modern requirements for randomized clinical trials. Often the diagnosis of migraine is not certain, the duration of treatment is too short, and the intervention is not clearly defined; furthermore, the control of treatment is insufficient. The study results are controversial regarding the efficiency of sports intervention in migraine. Regular exercises may have specific effects on the course of disease in migraine through increase of fitness or relaxing effects. It remains unclear whether exercise alone is efficient in migraine treatment or only as part of a more multidisciplinary program. Theoretical considerations, the available limited studies, and clinical experience suggest that exercise may have an effect on migraine, but the present knowledge does not fulfill the needs of evidence-based medicine. Future studies should adhere to the rules for randomized clinical trials in pharmacological migraine prophylaxis.

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Literatur

  1. (2007) Alles über Migräne – nicht medikamentöse Behandlungsverfahren. http://www.migraene-aktuell.de

  2. (2004) Beweg-Gründe – Sport hilft dem Kopf. http://www.focus.de/gesundheit/ratgeber/kopfschmerz/news

  3. (2007) Zehn Punkte gegen Migräne. http://www.aktivgegenmigraene.de

  4. Armstrong LE, Casa DJ, Millard-Stafford M et al. (2007) American College of Sports Medicine position stand. Exertional heat illness during training and competition. Med Sci Sports Exerc 39: 556–572

    Article  PubMed  Google Scholar 

  5. Armstrong LE, van Heest JL (2002) The unknown mechanism of the overtraining syndrome: clues from depression and psychoneuroimmunology. Sports Med 32: 185–209

    Article  PubMed  Google Scholar 

  6. Arraiz GA, Wigle DT, Mao Y (1992) Risk assessment of physical activity and physical fitness in the Canada Health Survey mortality follow-up study. J Clin Epidemiol 45: 419–428

    Article  PubMed  CAS  Google Scholar 

  7. Bartsch T (2006) Anstrengungskopfschmerzen. Akt Neurol 33: 11–19

    Article  Google Scholar 

  8. Bigal ME, Lipton RB (2006) Obesity is a risk factor for transformed migraine but not chronic tension-type headache. Neurology 67: 252–257

    Article  PubMed  Google Scholar 

  9. Blau JN, Kell CA, Sperling JM (2004) Water-deprivation headache: a new headache with two variants. Headache 44: 79–83

    Article  PubMed  Google Scholar 

  10. Burtscher M, Likar R, Nachbauer W, Philadelphy M (1998) Aspirin for prophylaxis against headache at high altitudes: randomised, double blind, placebo controlled trial. BMJ 316: 1057–1058

    PubMed  CAS  Google Scholar 

  11. Campello M, Nordin M, Weiser S (1996) Physical exercise and low back pain. Scand J Med Sci Sports 6: 63–72

    Article  PubMed  CAS  Google Scholar 

  12. Carlow T, Appenzeller O (1981) Neurology and endurance training. In: Appenzeller O, Atkinson R (eds) Sports medicine. Fitness training injuries. Urban & Fischer, München

  13. Colbert LH, Hootman JM, Macera CA (2000) Physical activity-related injuries in walkers and runners in the aerobics center longitudinal study. Clin J Sport Med 10: 259–263

    Article  PubMed  CAS  Google Scholar 

  14. Coris EE, Ramirez AM, van Durme DJ (2004) Heat illness in athletes: the dangerous combination of heat, humidity and exercise. Sports Med 34: 9–16

    Article  PubMed  Google Scholar 

  15. Darling M (1991) The use of exercise as a method of aborting migraine. Headache 31: 616–618

    Article  PubMed  CAS  Google Scholar 

  16. Dexter JD, Roberts J, Byer JA (1978) The five hour glucose tolerance test and effect of low sucrose diet in migraine. Headache 18: 91–94

    Article  PubMed  CAS  Google Scholar 

  17. Diener HC (2002) Migräne, vol 2. Thieme, Stuttgart, S 89

  18. Diener HC, Brune K, Gerber W et al. (2000) Therapie der Migräneattacke und Migräeprophylaxe. Empfehlungen der Deutschen Migräne- und Kopfschmerzgesellschaft (DMKG) in Kooperation mit der Kommission „Schmerztherapie“ der Deutschen Gesellschaft für Neurologie (DGN). http://www.dgn.org

  19. Dishman R (1982) Compliance/adherence in health-related exercise. Health Psychol 1: 237–267

    Article  Google Scholar 

  20. Dooley JM, Gordon KE, Wood EP, Brna PM (2006) Activity levels among adolescents with migraine. Pediatr Neurol 35: 119–121

    Article  PubMed  Google Scholar 

  21. Dubbert PM, Martin JE, Cushman WC et al. (1994) Endurance exercise in mild hypertension: effects on blood pressure and associated metabolic and quality of life variables. J Hum Hypertens 8: 265–272

    PubMed  CAS  Google Scholar 

  22. Evers S (2006) Fakten. Migräne, vol 1. Thieme, Stuttgart, S 70

  23. Fischer H, Heller R, Giesler A, Hollmann W (1994) Ausdauertraining bei Migräne: eine Pilotstudie. In: Liesen H, Weiß M, Baum H (Hrsg) Regulations- und Repairmechanismen. 33. Deutscher Sportärztekongress. Deutscher Ärzteverlag, Paderborn Köln, S 807–808

  24. Fitterling JM, Martin JE, Gramling S et al. (1988) Behavioral management of exercise training in vascular headache patients: an investigation of exercise adherence and headache activity. J Appl Behav Anal 21: 9–19

    Article  PubMed  CAS  Google Scholar 

  25. Fleg JL, Pina IL, Balady GJ et al. (2000) Assessment of functional capacity in clinical and research applications: an advisory from the Committee on Exercise, Rehabilitation, and Prevention, Council on Clinical Cardiology, American Heart Association. Circulation 102: 1591–1597

    PubMed  CAS  Google Scholar 

  26. Fradkin AJ, Finch CF, Sherman CA (2001) Warm up practices of golfers: are they adequate? Br J Sports Med 35: 125–127

    Article  PubMed  CAS  Google Scholar 

  27. Fresenius M, Hatzenbühler M, Hick M(2004) Repititorium Schmerzmedizin, vol 1. Springer, Berlin Heidelberg New York, S 131

  28. Gerber W, Miltner W, Gabler H et al. (1987) Bewegungs- und Sporttherapie bei chronischen Kopfschmerzen. In: Gerber W, Miltner W, Mayer K (Hrsg) Vorgebnisse und Perspektiven interdisziplinärer Forschung. edition medizin, S 55–66

  29. Göbel H (2007) Bringen Sie Bewegung in ihr Leben. http://www.migraene-schule.de/html/verhalten

  30. Grimm L, Douglas D, Hanson P (1981) Aerobic training in the prophylaxis of migraine. Med Sci Sports Exerc 13: 98

    Google Scholar 

  31. Hadorn DC, Baker D, Hodges JS, Hicks N (1996) Rating the quality of evidence for clinical practice guidelines. J Clin Epidemiol 49: 749–754

    Article  PubMed  CAS  Google Scholar 

  32. Hage P (1981) Exercise may reduce frequency of migraine. Phys Sports Med 9: 24–25

    Google Scholar 

  33. Haier RJ, Quaid K, Mills JC (1981) Naloxone alters pain perception after jogging. Psychiatry Res 5: 231–232

    Article  PubMed  CAS  Google Scholar 

  34. Hickson R (1981) Time course of the adaptation response of aerobic power and heart rate to training. Med Sci Sports Exerc 13: 17–20

    PubMed  CAS  Google Scholar 

  35. Holmstrom E, Ahlborg B (2005) Morning warming-up exercise – effects on musculoskeletal fitness in construction workers. Appl Ergon 36: 513–9

    Article  PubMed  Google Scholar 

  36. Holroyd K, Penzien D (1990) Pharmacological versus non-pharmacological prophylaxis of recurrent migraine headache: a meta-analytic review of clinical trials. Pain 42: 1–13

    Article  PubMed  CAS  Google Scholar 

  37. International Headache Society HCC (2004) Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Cephalalgia 24 [suppl 1]: 1–160

  38. Janal MN, Colt EW, Clark WC, Glusman M (1984) Pain sensitivity, mood and plasma endocrine levels in man following long-distance running: effects of naloxone. Pain 19: 13–25

    Article  PubMed  CAS  Google Scholar 

  39. Jokl E (1975) The contribution of sports medicine to clinical cardiology. Am Correct Ther J 29: 97–111

    PubMed  CAS  Google Scholar 

  40. Jost W, Selbach O (2001) Therapie der Migräne, vol 1. Uni-Med, Bremen London Boston, S 109

  41. Kemppainen P, Paalasmaa P, Pertovaara A et al. (1990) Dexamethasone attenuates exercise-induced dental analgesia in man. Brain Res 519: 329–332

    Article  PubMed  CAS  Google Scholar 

  42. Kirshner B (1984) Exercise – better than aspirin? Fit 4: 35

    Google Scholar 

  43. Kjellman GV, Skargren EI, Oberg BE (1999) A critical analysis of randomised clinical trials on neck pain and treatment efficacy. A review of the literature. Scand J Rehabil Med 31: 139–152

    Article  PubMed  CAS  Google Scholar 

  44. Koseoglu E, Akboyraz A, Soyuer A, Ersoy AO (2003) Aerobic exercise and plasma beta endorphin levels in patients with migrainous headache without aura. Cephalalgia 23: 972–976

    Article  PubMed  CAS  Google Scholar 

  45. Kumar KK (1988) Exercise for prophylaxis of migraine. Headache 28: 228

    Article  PubMed  CAS  Google Scholar 

  46. Kunkel R (1985) The role of exercise in the relief of head and neck pain. National Migraine Foundation Newsletter 55: 1–4

    Google Scholar 

  47. Kurns R, Turk D, Rudy T (1985) The West Haven-Yale Multidimensional Pain Inventory. Pain 23: 345–356

    Article  Google Scholar 

  48. Lambert RW jr, Burnet DL (1985) Prevention of exercise induced migraine by quantitative warm-up. Headache 25: 317–319

    Article  PubMed  Google Scholar 

  49. Lee IM, Hsieh CC, Paffenbarger RS jr (1995) Exercise intensity and longevity in men. The Harvard Alumni Health Study. JAMA 273: 1179–1184

    Article  PubMed  CAS  Google Scholar 

  50. Lemstra M, Stewart B, Olszynski WP (2002) Effectiveness of multidisciplinary intervention in the treatment of migraine: a randomized clinical trial. Headache 42: 845–854

    Article  PubMed  Google Scholar 

  51. Lockett DM, Campbell JF (1992) The effects of aerobic exercise on migraine. Headache 32: 50–54

    Article  PubMed  CAS  Google Scholar 

  52. Malm C, Nyberg P, Engstrom M et al. (2000) Immunological changes in human skeletal muscle and blood after eccentric exercise and multiple biopsies. J Physiol 529: 243–262

    Article  PubMed  CAS  Google Scholar 

  53. Mannion AF, Muntener M, Taimela S, Dvorak J (1999) A randomized clinical trial of three active therapies for chronic low back pain. Spine 24: 2435–2448

    Article  PubMed  CAS  Google Scholar 

  54. Marti B, Goerre S, Spuhler T et al. (1989) [Sudden death during mass running events in Switzerland 1978–1987: an epidemiologico-pathologic study]. Schweiz Med Wochenschr 119: 473–482

    PubMed  CAS  Google Scholar 

  55. Martin JE, Dubbert PM (1985) Adherence to exercise. In: Terjung R (ed) Exercise and sport sciences reviews. MacMillan, New York

  56. Martin JE, Dubbert PM (1987) The role of exercise in preventing and moderating blood pressure elevation. Bibl Cardiol 41: 120–142

    PubMed  CAS  Google Scholar 

  57. Martin PR, Seneviratne HM (1997) Effects of food deprivation and a stressor on head pain. Health Psychol 16: 310–318

    Article  PubMed  CAS  Google Scholar 

  58. Martins IP, Gouveia RG (2007) More on water and migraine. Cephalalgia 27: 372–374

    Article  PubMed  CAS  Google Scholar 

  59. McCrory P (2000) Headaches and exercise. Sports Med 30: 221–229

    Article  PubMed  CAS  Google Scholar 

  60. McCrory P, Penzien D, Rains J, Hasselblad V (1996) Efficacy of behavioral treatments ofor migraine and tension-type heacache: meta-analysis of controlled trials. Headache 36: 272

    Google Scholar 

  61. Melzack R (1975) The McGill Pain Questionnaire: major properties and scoring methods. Pain 1: 277–299

    Article  PubMed  CAS  Google Scholar 

  62. Narin SO, Pinar L, Erbas D et al. (2003) The effects of exercise and exercise-related changes in blood nitric oxide level on migraine headache. Clin Rehabil 17: 624–630

    Article  PubMed  Google Scholar 

  63. Neusüss K, Neumann B, Steinhoff BJ et al. (1997) Physical activity and fitness in patients with headache disorders. Int J Sports Med 18: 607–611

    Article  PubMed  Google Scholar 

  64. Oldridge NB, Guyatt GH, Fischer ME, Rimm AA (1988) Cardiac rehabilitation after myocardial infarction. Combined experience of randomized clinical trials. JAMA 260: 945–950

    Article  PubMed  CAS  Google Scholar 

  65. Oxman AD, Cook DJ, Guyatt GH (1994) Users‘ guides to the medical literature. VI. How to use an overview. Evidence-Based Medicine Working Group. JAMA 272: 1367–1371

    Article  PubMed  CAS  Google Scholar 

  66. Paffenbarger RS jr, Hyde RT, Wing AL, Hsieh CC (1986) Physical activity, all-cause mortality, and longevity of college alumni. N Engl J Med 314: 605–613

    Article  PubMed  Google Scholar 

  67. Pertovaara A, Huopaniemi T, Virtanen A, Johansson G (1984) The influence of exercise on dental pain thresholds and the release of stress hormones. Physiol Behav 33: 923–926

    Article  PubMed  CAS  Google Scholar 

  68. Pokan R, Hofmann P, Wonisch M, Hörtnagel H (2004) Funktionsdiagnotstik akuter und chronischer Anpassung des Herz-Kreislaufsystems an körperliche Belastungen. In: Pokan R, Förster H, Hofmann P et al. (Hrsg) Kompendium der Sportmedizin. Springer, Berlin Heidelberg New York, S 45–81

  69. Powell B (1982) Weight lifter’s cephalgia. Ann Emerg Med 11: 449–451

    Article  PubMed  CAS  Google Scholar 

  70. Reimers C, Brooks A (2002) Neurologie, Psychiatrie und Sport. Thieme, Stuttgart

  71. Robbins L (1994) Precipitating factors in migraine: a retrospective review of 494 patients. Headache 34: 214–216

    Article  PubMed  CAS  Google Scholar 

  72. Rost R (1988) [Sudden non-traumatic death in sports. 2. Risk factors and recommendations for prevention]. Fortschr Med 106: 131–134

    PubMed  CAS  Google Scholar 

  73. Rost R (1988) [Sudden, non-traumatic death in sports. 1: Incidence and causes]. Fortschr Med 106: 103–106

    PubMed  CAS  Google Scholar 

  74. Sackett D (1995) Evidence-based medicine. Lancet 346: 1171

    Article  PubMed  CAS  Google Scholar 

  75. Sallis RE, Jones K (2000) Prevalence of headaches in football players. Med Sci Sports Exerc 32: 1820–1824

    Article  PubMed  CAS  Google Scholar 

  76. Senn S, D’Angelo G, Potvin D (2004) Carry-over in cross-over trials in bioequivalence: theoretical concerns and empirical evidence. Pharmaceut Statist 3: 133–142

    Article  Google Scholar 

  77. Simons A, Solbach P, Sargent J, Malone L (1986) A wellness program in the treatment of headache. Headache 26: 343–352

    Article  PubMed  CAS  Google Scholar 

  78. Sjaastad O, Bakketeig LS (2002) Exertional headache. I. Vaga study of headache epidemiology. Cephalalgia 22: 784–790

    Article  PubMed  CAS  Google Scholar 

  79. Sjaastad O, Bakketeig LS (2003) Exertional headache. II. Clinical features Vaga study of headache epidemiology. Cephalalgia 23: 803–807

    Article  PubMed  CAS  Google Scholar 

  80. Sjaastad O, Bakketeig LS (2003) Prolonged benign exertional headache. The Vaga Study of headache epidemiology. Headache 43: 611–615

    Article  PubMed  CAS  Google Scholar 

  81. Slattery ML, Jacobs DR jr (1988) Physical fitness and cardiovascular disease mortality. The US Railroad Study. Am J Epidemiol 127: 571–580

    PubMed  CAS  Google Scholar 

  82. Smekal G, Samitz G, Schmid P (2004) Nutzen und Risiken körperlicher Aktivität – epidemiologische Aspekte. In: Pokan R, Förster H, Hofmann P et al. (Hrsg) Kompendium der Sportmedizin. Springer, Berlin Heidelberg New York, S 1–16

  83. Sternberg WF, Bailin D, Grant M, Gracely RH (1998) Competition alters the perception of noxious stimuli in male and female athletes. Pain 76: 231–238

    Article  PubMed  CAS  Google Scholar 

  84. Subcommittee IHSCT (2000) Guidelines for controlled trials of drugs in migraine: second edition. Cephalalgia 20: 765–786

    Article  Google Scholar 

  85. Suter TM, Hess OM, Bortone A et al. (1989) Coronary stenosis vasomotion during dynamic exercise before and after PTCA. Eur Heart J 10 [suppl G]: 58–63

  86. Tait R, Chibnell J, Krause S (1990) The Pain Disability Index: psychometric properties. Pain 40: 171–182

    Article  PubMed  CAS  Google Scholar 

  87. Thompson JK (1987) Exercise-induced migraine prodrome symptoms. Headache 27: 250–251

    Article  PubMed  CAS  Google Scholar 

  88. Van Gijn J (1987) Relief of common migraine by exercise. J Neurol Neurosurg Psychiatry 50: 1700–1701

    Google Scholar 

  89. Vecchiet L, Marini I, Colozzi A, Feroldi P (1984) Effects of aerobic exercise on muscular pain sensitivity. Clin Ther 6: 354–363

    PubMed  CAS  Google Scholar 

  90. Vuori I (1986) The cardiovascular risks of physical activity. Acta Med Scand 711 [suppl]: 205–214

    Google Scholar 

  91. Williams M (2004) Exercise: a new migraine headache therapy. Healthnote Newswire 4

  92. Williams SJ, Nukada H (1994) Sport and exercise headache: part 2. Diagnosis and classification. Br J Sports Med 28: 96–100

    Article  PubMed  CAS  Google Scholar 

  93. Ylinen J, Takala EP, Nykanen M et al. (2003) Active neck muscle training in the treatment of chronic neck pain in women: a randomized controlled trial. JAMA 289: 2509–2516

    Article  PubMed  Google Scholar 

  94. Zakas A, Doganis G, Zakas N, Vergou A (2006) Acute effects of active warm-up and stretching on the flexibility of elderly women. J Sports Med Phys Fitness 46: 617–622

    PubMed  CAS  Google Scholar 

  95. Zakas A, Grammatikopoulou MG, Zakas N et al. (2006) The effect of active warm-up and stretching on the flexibility of adolescent soccer players. J Sports Med Phys Fitness 46: 57–61

    PubMed  CAS  Google Scholar 

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Busch, V., Gaul, C. Sport bei Migräne. Schmerz 22, 137–147 (2008). https://doi.org/10.1007/s00482-007-0586-8

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