Abstract
We report a 21-year-old male with childhood-onset familial nephrotic syndrome and frequent relapses who manifested toxicity or treatment resistance to corticosteroids, cyclophosphamide, cyclosporin-A, and tacrolimus. Monotherapy with mycophenolate mofetil (MMF) resulted in maintenance of clinical remission for 14 months without noticeable toxicity, while allowing resolution of steroid-induced side effects. Our observation suggests that MMF may be useful in maintaining remission in nephrotic patients who manifest toxicity to standard immunosuppressive agents.
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Received: 6 April 1999 / Revised: 10 August 1999 / Accepted: 13 August 1999
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Chandra, M., Susin, M. & Abitbol, C. Remission of relapsing childhood nephrotic syndrome with mycophenolate mofetil. Pediatr Nephrol 14, 224–226 (2000). https://doi.org/10.1007/s004670050047
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DOI: https://doi.org/10.1007/s004670050047