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Ambulatory blood pressure monitoring and renal functions in term small-for-gestational age children

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Abstract

The aim of this study was to investigate the relationship between birth weight and blood pressure (BP) by means of ambulatory BP monitoring (ABPM) and renal functions in non-obese children who were born small-for-gestational age (SGA) at term. The study group consisted of 39 (19 female, 20 male; mean age 8.8 ± 2.6 years) children born SGA. Their data were compared to those of 27 (13 female, 14 male; mean age 8.2 ± 2.9 years) children born appropriate-for-gestational age (AGA). No difference between SGA and AGA children was observed based on office BP measurements and daytime, nighttime and 24-h ABPM. Seventeen SGA (48.6%) and nine AGA (37.5%) children had a 24-h systolic BP (SBP) load over 25%, and seven of these (5 SGA, 2 AGA) were hypertensive according to mean SBP values. The prevalence of the non-dipping phenomenon in SGA and AGA children was similar. Renal functions were normal and similar in both groups. Three children (2 SGA, 1 AGA) with normal glomerular filtration rate had higher microalbumin excretion and one SGA child had systolic hypertension according to the office BP. Our findings demonstrate that the influence of intrauterine growth restriction on BP is not manifested during the childhood period, and they do not support the existence of a negative relationship between birth weight and BP in children.

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Acknowledgments

We would like to express our gratitude to NovoNordisk, Turkey for providing financial support for purchasing the kits.

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Authors and Affiliations

  1. Department of Pediatrics, Pediatric Nephrology Unit, Istanbul Faculty of Medicine, Istanbul University, Çapa-Istanbul, 34390, Turkey

    Ilmay Bilge, Sevinc Emre & Aydan Sirin

  2. Department of Pediatrics, Pediatric Endocrinology Unit, Istanbul Faculty of Medicine, Istanbul University, Çapa-Istanbul, 34390, Turkey

    Sukran Poyrazoglu, Firdevs Bas, Sema Eryilmaz & Feyza Darendeliler

  3. Department of Pediatrics, Istanbul Faculty of Medicine, Istanbul University, Çapa-Istanbul, 34390, Turkey

    Selman Gokalp

  4. Dr. Pakize I. Tarzi Laboratory, Istanbul, Turkey

    Nezih Hekim

  5. Çocuk Kliniği, İstanbul Tıp Fakültesi, Çapa-Istanbul, 34390, Turkey

    Feyza Darendeliler

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  1. Ilmay Bilge
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  2. Sukran Poyrazoglu
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Correspondence to Feyza Darendeliler.

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Bilge, I., Poyrazoglu, S., Bas, F. et al. Ambulatory blood pressure monitoring and renal functions in term small-for-gestational age children. Pediatr Nephrol 26, 119–126 (2011). https://doi.org/10.1007/s00467-010-1646-3

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  • DOI: https://doi.org/10.1007/s00467-010-1646-3

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