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Severe hypertension and massive proteinuria in a newborn with renal artery stenosis

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Abstract

Renal vein thrombosis and the congenital nephrotic syndrome have been associated with nephrotic-range proteinuria/nephrotic syndrome and hypertension in the newborn period. We describe a newborn with severe hypertension and proteinuria secondary to unilateral renal artery stenosis. Proteinuria completely disappeared with blood pressure control (with sodium nitroprusside and an angiotensin-converting enzyme inhibitor). Although renin was not measured, we speculate that proteinuria might have been induced by a high renin state, and was controlled by the angiotensin-converting enzyme inhibitor.

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Correspondence to François Cachat.

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Cachat, F., Bogaru, A., Micheli, JL. et al. Severe hypertension and massive proteinuria in a newborn with renal artery stenosis. Pediatr Nephrol 19, 544–546 (2004). https://doi.org/10.1007/s00467-003-1391-y

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  • DOI: https://doi.org/10.1007/s00467-003-1391-y

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