Abstract
Glomerular cysts can exist in the context of several different kidney diseases. Advances in the last few years have begun to unravel the genetic bases and pathogenesis of some of these entities, many of which have an origin in abnormal development. In this review, we highlight recent insights into three types of disease associated with glomerular cysts: (1) mutations of the hepatocyte nuclear factor 1β (HNF-1β) in the recently described renal cysts and diabetes syndrome, (2) mutations of OFD1 in the oral facial digital syndrome type 1 and (3) the role of fetal urinary tract obstruction.
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Received: 10 August 2001 / Revised: 7 December 2001 / Accepted: 10 December 2001
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Woolf, A., Feather, S. & Bingham, C. Recent insights into kidney diseases associated with glomerular cysts. Pediatr Nephrol 17, 229–235 (2002). https://doi.org/10.1007/s00467-001-0819-5
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DOI: https://doi.org/10.1007/s00467-001-0819-5