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True NOTES TME resection with splenic flexure release, high ligation of IMA, and side-to-end hand-sewn coloanal anastomosis

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Abstract

Introduction

Natural orifice transluminal endoscopic surgery (NOTES) represents the ultimate expression of minimally invasive surgery. We have developed and present here an initial feasibility and safety study of transanal total mesorectal excision (TME) with splenic flexure release, high ligation of the IMA and IMV, and side-to-end coloanal anastomosis with temporary diverting ileostomy for rectal cancer.

Methods

A program of full NOTES TME resection with release of the splenic flexure, high ligation of the IMA/IMV, with side-to-end coloanal anastomosis was performed transanally from December 2013 to July 2014. Demographics, preoperative, perioperative, and postoperative data were prospectively obtained. Operative components were broken into TME, colonic mobilization, splenic flexure release, IMA/IMV transection, transanal extraction of specimen, and coloanal anastomosis for analysis of performance completion.

Results

There were 3 women and 1 man on whom we operated. Mean age was 56 (46–65). Mean BMI was 26 (23.8–30.2). The operation was completed entirely transanally in 2 patients. Transanal component completion of the operation was as follows: TME in 3/4; colonic mobilization in 4/4; splenic flexure release in 3/4; IMA/IMV transection in 3/4; transanal specimen extraction in 4/4; coloanal anastomosis in 4/4. Abdominal time for completion of component parts was: splenic flexure release 4:53 (min:s), IMA/IMV 19:43, completion of TME 13:41. Mean EBL was 194 cc (25–500). Aside from stoma site, there were no abdominal incisions. There were no mortalities. Mesorectum was intact in all 4 patients and with negative circumferential and distal margins.

Conclusion

This experience supports the feasibility and safety of a true NOTES TME. The critical anatomic views demonstrated on video affirm the potential of this approach for distal rectal cancer. Colorectal surgery represents the most logical application for NOTES. While highly promising, a great deal of work remains to develop the technique and applicability of NOTES colorectal surgery.

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Authors and Affiliations

  1. Marks Colorectal Surgical Associates, Lankenau Institute for Medical Research, Wynnewood, PA, USA

    John H. Marks, Nicolas Lopez-Acevedo, Barath Krishnan, Matthew N. Johnson, Grace A. Montenegro & Gerald J. Marks

  2. Lankenau Medical Center, Medical Office Building West, Suite 330, 100 East Lancaster Avenue, Wynnewood, PA, 19096, USA

    John H. Marks

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  1. John H. Marks
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  2. Nicolas Lopez-Acevedo
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  3. Barath Krishnan
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  4. Matthew N. Johnson
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  5. Grace A. Montenegro
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  6. Gerald J. Marks
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Correspondence to John H. Marks.

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Drs. John Marks, Nicolas Lopez-Acevedo, Barath Krishnan, Grace Montenegro, Gerald Marks, and Mr. Matthew Johnson have no conflicts of interest or financial ties to disclose.

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Marks, J.H., Lopez-Acevedo, N., Krishnan, B. et al. True NOTES TME resection with splenic flexure release, high ligation of IMA, and side-to-end hand-sewn coloanal anastomosis. Surg Endosc 30, 4626–4631 (2016). https://doi.org/10.1007/s00464-015-4731-7

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  • DOI: https://doi.org/10.1007/s00464-015-4731-7

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