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Endoscopic retrograde appendicitis therapy (ERAT) : a multicenter retrospective study in China

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Abstract

Background

Endoscopic retrograde appendicitis therapy (ERAT) is a new procedure for the treatment of acute uncomplicated appendicitis. The aim of the study was to review the clinical outcomes of ERAT and further examine its effectiveness and safety.

Methods

The study was performed on patients who underwent ERAT for acute uncomplicated appendicitis at three tertiary hospitals in China from December 2009 to May 2013. Patient demographics, technique aspects of the ERAT procedures, clinical success (resolution of symptoms and normalization of laboratory tests), time until resumption of diet, and hospital stay were analyzed, and complications and recurrence were followed up.

Results

Forty-one patients were entered, among which 34 patients were definitely diagnosed as having acute uncomplicated appendicitis; in 7 patients, acute appendicitis was excluded by endoscopic retrograde appendicography. Thirty-three patients completed ERAT except one patient who failed appendiceal cannulation. Abdominal pain resolved immediately in 32 patients, and clinical success rate was 97 %. There was one failure case (3 %) that complicated perforation after 48 h received emergency appendectomy. The median follow-up period was 12 months (IQR = 9–23 months). During follow-up, there were no long-term complication; 2 patients (6.2 %) had recurrent abdominal pain and received appendectomy (one had a histologically normal appendix).

Conclusions

ERAT is an effective method to diagnose and treat acute uncomplicated appendicitis. Multicenter prospective clinical trials are needed to confirm its utility and place in the management of suspected acute appendicitis

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Acknowledgments

We express our gratitude to Professor David Y. Graham and Lovedip S. Kooner for their assistance in revising the manuscript.

Disclosures

Bing-Rong Liu, Xiao Ma, Jia Feng, Zhuo Yang, Bo Qu, Zi-Tan Feng, Shu-Ren Ma, Ji-Bin Yin, Rong Sun, Li–Li Guo, Wen-Ge Liu have no conflicts of interest or financial ties to disclose.

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Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, The Second Affiliated Hospital of Harbin Medical University, 246 Xue-Fu Road, Nan-Gang District, Harbin, 150086, China

    Bing-Rong Liu, Xiao Ma, Bo Qu & Ji-Bin Yin

  2. Department of Gastroenterology and Hepatology, Betune International Peace Hospital, Shijiazhuang, 050000, China

    Jia Feng, Zi-Tan Feng, Rong Sun, Li-Li Guo & Wen-Ge Liu

  3. Department of Endoscopy, Shenyang North Hospital, Shenyang, 110000, China

    Zhuo Yang & Shu-Ren Ma

Authors
  1. Bing-Rong Liu
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  2. Xiao Ma
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  3. Jia Feng
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  4. Zhuo Yang
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  5. Bo Qu
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  6. Zi-Tan Feng
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  7. Shu-Ren Ma
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  8. Ji-Bin Yin
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  9. Rong Sun
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  10. Li-Li Guo
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  11. Wen-Ge Liu
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Corresponding author

Correspondence to Bing-Rong Liu.

Additional information

Bing-Rong Liu contributed equally with Xiao Ma and is the co-first author for this paper.

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Liu, BR., Ma, X., Feng, J. et al. Endoscopic retrograde appendicitis therapy (ERAT) : a multicenter retrospective study in China. Surg Endosc 29, 905–909 (2015). https://doi.org/10.1007/s00464-014-3750-0

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  • DOI: https://doi.org/10.1007/s00464-014-3750-0

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