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Endosonography-guided transmural drainage of pancreatic pseudocysts using an exchange-free access device: initial clinical experience

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Abstract

Background

Endosonography (EUS)-guided transmural pseudocyst drainage is a multistep procedure currently performed with different “off-the-shelf” accessories developed for other applications. Multiple device exchanges over-the-wire is time consuming and risks loss of wire access. This report describes the technical feasibility and outcomes for EUS-guided drainage of pancreatic fluid collections using a novel exchange-free device developed for translumenal therapy.

Methods

Between April and November 2010, 14 patients (9 men; mean age, 49.9 years) with pancreatic fluid collection (mean size, 102 mm) underwent 16 EUS-guided drainage procedures using the exchange-free access device at a single tertiary care center. The trocar of the exchange-free device was used to gain pseudocyst access. The dual-balloon catheter then was advanced over the trocar, followed by inflation of the (first) anchor balloon. Cyst contents were sampled, and contrast was injected to define the pseudocyst anatomy. The first guidewire was inserted into the cyst cavity. The cystenterostomy tract was dilated to 10 mm with the (second) dilation balloon, followed by a second guidewire insertion. The exchange-free access device was removed, leaving the two guidewires in place for two double-pigtail stents.

Results

The procedure was technically successful for all the patients. No acute procedure-related complications occurred. Late complications included a symptomatic leak in a patient who underwent drainage of a pancreatic uncinate pseudocyst from the second duodenum, a self-limited transfusion-dependent bleed after transbulbar drainage, and symptomatic pseudocyst infection.

Conclusion

Pseudocyst access, cystenterostomy tract dilation, and placement of two guidewires for dual stent drainage are technically feasible using an exchange-free access device. The device has the potential to standardize, simplify, and streamline EUS-guided pseudocyst drainage with a single instrument. Comparative studies with alternative tools and methods for pseudocyst drainage are warranted.

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Disclosures

Kenneth F. Binmoeller is a consultant (chief medical officer) with an equity interest in Xlumena, Inc. Janak N. Shah is a consultant and advisory board member of Xlumena, Inc. Frank Weilert, Yasser Bhat, and Steve Kane have no conflicts of interest or financial ties to disclose.

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Correspondence to Kenneth F. Binmoeller.

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Binmoeller, K.F., Weilert, F., Shah, J.N. et al. Endosonography-guided transmural drainage of pancreatic pseudocysts using an exchange-free access device: initial clinical experience. Surg Endosc 27, 1835–1839 (2013). https://doi.org/10.1007/s00464-012-2682-9

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  • DOI: https://doi.org/10.1007/s00464-012-2682-9

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