Skip to main content

Advertisement

Log in

Percutaneous transhepatic insertion of self-expanding short metal stents for biliary obstruction before resection of pancreatic or duodenal malignancy proves to be safe and effective

  • Published:
Surgical Endoscopy Aims and scope Submit manuscript

Abstract

Background

The British Society of Gastroenterology guidelines for the management of malignant obstructive jaundice state: “If a stent is placed prior to surgery, this should be of the plastic type and it should be placed endoscopically. Self-expanding metal stents should not be inserted in patients who are likely to proceed to resection.” In 2003, a small series of complications after endoscopic intervention caused a change in the authors’ practice. Currently, all patients requiring relief of biliary obstruction before surgical resection undergo attempted insertion of a short metal biliary stent.

Methods

Retrospective analysis of the authors’ prospective database containing all patients presenting with periampullary and pancreatic tumors between January 2004 and May 2008 was performed.

Results

The authors have attempted percutaneous placement of internal metal stents in 67 patients with resectable malignancies and biliary obstruction. Stenting was successful for 53 patients (79%), and 5 patients (9.4%) experienced complications. These five patients were successfully managed conservatively, and all proceeded to trial dissection. The mean bilirubin level was 253 mg/dl before intervention and 33 mg/dl before surgery for the stented patients compared with 308 mg/dl before intervention and 102 mg/dl before surgery for those who needed external drainage.

Conclusions

Percutaneous insertion of short metal stents provides a safe and effective alternative to endoscopic stent placement for treating jaundice preoperatively in patients with potentially resectable tumors around the pancreatic head.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Pancreatric Section, British Society of Gastroenterology; Pancreatic Society of Great Britain and Ireland; Association of Upper Gastrointestinal Surgeons of Great Britain and Ireland; Royal College of Pathologists; Special Interest Group for Gastro-Intestinal Radiology (2005) Guidelines for the management of patients with pancreatic cancer periampullary and ampullary carcinomas. Gut 54(suppl 5):v1–v16

    Article  Google Scholar 

  2. Gouma DJ, Nieveen van Dijkum EJ, Obertop H (1999) The standard diagnostic workup and surgical treatment of pancreatic head tumours. Eur J Surg Oncol 25:113–123

    Article  CAS  PubMed  Google Scholar 

  3. Povoski SP, Karpeh MS Jr, Conlon KC, Blumgart LH, Brennan MF (1999) Association of preoperative biliary drainage with postoperative outcome following pancreaticoduodenectomy. Ann Surg 230:131–142

    Article  CAS  PubMed  Google Scholar 

  4. Gouma DJ, Coelho JC, Fisher JD, Schlegel JF, Li YF, Moody FG (1986) Endotoxemia after relief of biliary obstruction by internal and external drainage in rats. Am J Surg 151:476–479

    Article  CAS  PubMed  Google Scholar 

  5. Klinkenbijl JH, Jeekel J, Schmitz PI, Rombout PA, Nix GA, Bruining HA et al (1993) Carcinoma of the pancreas and periampullary region: palliation versus cure. Br J Surg 80:1575–1578

    Article  CAS  PubMed  Google Scholar 

  6. Gouma DJ, Roughneen PT, Kumar S, Moody FG, Rowlands BJ (1986) Changes in nutritional status associated with obstructive jaundice and biliary drainage in rats. Am J Clin Nutr 44:362–369

    CAS  PubMed  Google Scholar 

  7. Lai EC, Mok FP, Fan ST, Lo CM, Chu KM, Liu CL et al (1994) Preoperative endoscopic drainage for malignant obstructive jaundice. Br J Surg 81:1195–1198

    Article  CAS  PubMed  Google Scholar 

  8. van der Gaag NA, de Castro SM, Rauws EA, Bruno MJ, van Eijck CH, Kuipers EJ et al (2007) Preoperative biliary drainage for periampullary tumors causing obstructive jaundice: DRainage vs. (direct) OPeration (DROP-trial). BMC Surg 7:3

    Article  PubMed  Google Scholar 

  9. Roughneen PT, Gouma DJ, Kulkarni AD, Fanslow WF, Rowlands BJ (1986) Impaired specific cell-mediated immunity in experimental biliary obstruction and its reversibility by internal biliary drainage. J Surg Res 41:113–125

    Article  CAS  PubMed  Google Scholar 

  10. Mumtaz K, Hamid S, Jafri W (2007) Endoscopic retrograde cholangiopancreaticography with or without stenting in patients with pancreaticobiliary malignancy, prior to surgery. Cochrane Database Syst Rev (3):CD006001

  11. Smith RA, Dajani K, Dodd S, Whelan P, Raraty M, Sutton R et al (2008) Preoperative resolution of jaundice following biliary stenting predicts more favourable early survival in resected pancreatic ductal adenocarcinoma. Ann Surg Oncol 15:3138–3146

    Article  PubMed  Google Scholar 

  12. Lawrence C, Howell DA, Conklin DE, Stefan AM, Martin RF (2006) Delayed pancreaticoduodenectomy for cancer patients with prior ERCP-placed, nonforeshortening, self-expanding metal stents: a positive outcome. Gastrointest Endosc 63:804–807

    Article  PubMed  Google Scholar 

  13. Hodul P, Creech S, Pickleman J, Aranha GV (2003) The effect of preoperative biliary stenting on postoperative complications after pancreaticoduodenectomy. Am J Surg 186:420–425

    Article  PubMed  Google Scholar 

  14. Jagannath P, Dhir V, Shrikhande S, Shah RC, Mullerpatan P, Mohandas KM (2005) Effect of preoperative biliary stenting on immediate outcome after pancreaticoduodenectomy. Br J Surg 92:356–361

    Article  CAS  PubMed  Google Scholar 

  15. Gerke H, White R, Byrne MF, Stiffier H, Mitchell RM, Hurwitz HI et al (2004) Complications of pancreaticoduodenectomy after neoadjuvant chemoradiation in patients with and without preoperative biliary drainage. Dig Liver Dis 36:412–418

    CAS  PubMed  Google Scholar 

  16. Sewnath ME, Karsten TM, Prins MH, Rauws EJ, Obertop H, Gouma DJ (2002) A metaanalysis on the efficacy of preoperative biliary drainage for tumors causing obstructive jaundice. Ann Surg 236:17–27

    Article  PubMed  Google Scholar 

  17. Pinol V, Castells A, Bordas JM, Real MI, Llach J, Montana X et al (2002) Percutaneous self-expanding metal stents versus endoscopic polyethylene endoprostheses for treating malignant biliary obstruction: randomized clinical trial. Radiology 225:27–34

    Article  PubMed  Google Scholar 

  18. Speer AG, Cotton PB, Russell RC, Mason RR, Hatfield AR, Leung JW et al (1987) Randomised trial of endoscopic versus percutaneous stent insertion in malignant obstructive jaundice. Lancet 2:57–62

    Article  CAS  PubMed  Google Scholar 

  19. Guo YX, Li YH, Chen Y, Chen PY, Luo PF, Li Y et al (2003) Percutaneous transhepatic metal versus plastic biliary stent in treating malignant biliary obstruction: a multiple center investigation. Hepatobiliary Pancreat Dis Int 2:594–597

    PubMed  Google Scholar 

  20. Mullen JT, Lee JH, Gomez HF, Ross WA, Fukami N, Wolff RA et al (2005) Pancreaticoduodenectomy after placement of endobiliary metal stents. J Gastrointest Surg 9:1094–1104; discussion 1104–1105

    Article  PubMed  Google Scholar 

  21. Huibregtse K (1996) Complications of endoscopic sphincterotomy and their prevention. N Engl J Med 335:961–963

    Article  CAS  PubMed  Google Scholar 

  22. Cotton PB, Lehman G, Vennes J, Geenen JE, Russell RC, Meyers WC et al (1991) Endoscopic sphincterotomy complications and their management: an attempt at consensus. Gastrointest Endosc 37:383–393

    Article  CAS  PubMed  Google Scholar 

  23. Wasan SM, Ross WA, Staerkel GA, Lee JH (2005) Use of expandable metallic biliary stents in resectable pancreatic cancer. Am J Gastroenterol 100:2056–2061

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We acknowledge the assistance of Mr. A. W. Majeed and Mr. A. Wyman.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Christopher D. Briggs.

Additional information

Presented as a poster presentation at the Association of Upper Gastrointestinal Surgeons, Liverpool, September 2009 and The European Hepatopancreato Biliary Association, Athens, June 2009.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Briggs, C.D., Irving, G.R.B., Cresswell, A. et al. Percutaneous transhepatic insertion of self-expanding short metal stents for biliary obstruction before resection of pancreatic or duodenal malignancy proves to be safe and effective. Surg Endosc 24, 567–571 (2010). https://doi.org/10.1007/s00464-009-0598-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00464-009-0598-9

Keywords

Navigation