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Gastrointestinal stromal tumors (GIST) and laparoscopic resection

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Abstract

Aim

To review management, outcome and the lessons learnt from a laparoscopic approach to GISTs.

Method

All cases of GIST presenting to the upper GI MDT between 2000 and 2006 were reviewed. Presentation, preoperative investigations, management and follow-up were recorded. Surgical resection using a laparoscopic approach, where feasible was the preferred management.

Results

25 consecutive patients that included one oesophageal, three oesophago-gastric, 19 gastric and two smallbowel GISTs were treated between 2000 and 2006. There were 11 male and 14 females with a median age of 68 (25–90) years. Clinical presentation was: gastrointestinal bleed 15, pain 6, dysphagia 2, anaemia 3, weight loss 1, and asymptomatic 2. Out of 25, four were inoperable and treated with imatinib. 17 laparoscopic (including 2 conversions) and four open procedures were performed. Two (both GISTs close to the oesophago-gastric junction) required reoperation due to surgical-related morbidity. Of the 25, five were high-, 11 intermediate- and nine low-risk GISTs. No recurrences in follow-up (median 24, range 6–75) months was observed.

Conclusion

GISTs can safely and effectively be treated laparoscopically although larger GISTs in difficult anatomical locations may require open surgery.

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Authors and Affiliations

  1. Upper Gastrointestinal Unit, Royal Bournemouth Hospital, Castle Lane East, Bournemouth, BH7 7DW, United Kingdom

    Sanjoy Basu, Sam Balaji, David H. Bennett & Nick Davies

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  1. Sanjoy Basu
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  2. Sam Balaji
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  4. Nick Davies
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Correspondence to Sanjoy Basu.

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Basu, S., Balaji, S., Bennett, D.H. et al. Gastrointestinal stromal tumors (GIST) and laparoscopic resection. Surg Endosc 21, 1685–1689 (2007). https://doi.org/10.1007/s00464-007-9445-z

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