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Radiofrequency tissue ablation in an experimental model of grade IV renal trauma: a preliminary report

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Abstract

Background

The kidney is one of the most frequently injured intraabdominal organs. In this study, we investigated the efficacy and safety of radiofrequency ablation (RFA) as a kidney-preserving hemostatic technique for grade IV renal trauma.

Methods

A grade IV injury was induced in the right kidney of 12 Landrace pigs. Then RFA was applied around the injury in 10 animals until hemostasis was achieved; two animals were not treated (control group). The treated animals were killed humanely on days 0, 3, 7, 14 and 21 and examined. The kidneys were subjected to histologic and radiologic examination.

Results

The two untreated animals died from hypovolemic shock. Hemostasis was achieved in all treated animals. We had no operative deaths and no morbidity. No blood, pus, urine, or other fluid was found at the time of death. In one animal, a fistulous lesion leading to the collecting system was identified, but no urine leakage was observed. At histology, the ablated areas were found to consist of three zones: an inner necrotic one, a zone of neutrophils digesting necrotic tissue, and an outer zone with possibly reversible damage.

Conclusions

Radiofrequency ablation is an efficient and safe hemostatic method for grade IV renal trauma. Further study is needed to investigate the possible application of this method to humans and its percutaneous or laparoscopic use.

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Authors and Affiliations

  1. First Department of Surgery, University of Athens, Laiko General Hospital, 17 Agiou Thoma Street, 11527, Athens, Greece

    M. Kontos, E. Felekouras, E. Pikoulis, F. Sigala, A. Papalois, E. Papalambros & E. Bastounis

  2. Pathology Department, University of Athens, Laiko General Hospital, 17 Agiou Thoma Street, 11527, Athens, Greece

    E. Drakos & D. Hatzianastasiou

  3. Department of Urology, University of Athens, Laiko General Hospital, 17 Agiou Thoma Street, 11527, Athens, Greece

    D. Mitropoulos

  4. Department of Anesthesiology, University of Athens, Laiko General Hospital, 17 Agiou Thoma Street, 11527, Athens, Greece

    C. Staikou

Authors
  1. M. Kontos
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  2. E. Felekouras
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  3. E. Drakos
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  4. E. Pikoulis
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  5. D. Mitropoulos
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  6. C. Staikou
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  7. D. Hatzianastasiou
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  8. F. Sigala
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  9. A. Papalois
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  10. E. Papalambros
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  11. E. Bastounis
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Corresponding author

Correspondence to E. Pikoulis.

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Kontos, M., Felekouras, E., Drakos, E. et al. Radiofrequency tissue ablation in an experimental model of grade IV renal trauma: a preliminary report. Surg Endosc 19, 249–253 (2005). https://doi.org/10.1007/s00464-003-9327-y

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  • DOI: https://doi.org/10.1007/s00464-003-9327-y

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