Skip to main content
Log in

Results after endoscopic treatment of postoperative upper gastrointestinal fistulas and leaks using combined Vicryl plug and fibrin glue

  • Original article
  • Published:
Surgical Endoscopy And Other Interventional Techniques Aims and scope Submit manuscript

Abstract

Background

The incidence of clinically relevant anastomotic leaks after upper gastrointestinal surgery is approximately 4% to 20%, and the associated mortality is up to 80%. Depending on the clinical presentation, the treatment options include surgery, conservative treatment with or without external drainage or endoscopic treatment.

Methods

This report presents nine cases of anastomotic leaks or fistulae after surgery for upper gastrointestinal cancers that were treated by insertion of a Vicryl plug and sealing with fibrin glue. Under sedation, all nine patients underwent endoscopic lavage of the cavity at the site of anastomotic leakage. The entrance to the cavity then was filled with Vicryl mesh and sealed off with fibrin glue. After the procedure, the patients underwent endoscopy and a water-soluble contrast study for assessment of the result.

Results

Seven of the nine patients had complete healing of the anastomotic leak or fistula after one to two endoscopic treatments. In one case, the treatment failed immediately because of a large and direct tracheoesophageal fistula. Another patient experienced recurrent intrathoracic abscesses after initial technical success.

Conclusions

Postoperative upper gastrointestinal fistulas or anastomotic leaks can be managed successfully with little morbidity by means of endoscopic insertion of Vicryl mesh with fibrin glue, thereby avoiding repetitive major surgery and its associated risks.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1
Figure 2
Figure 3

Similar content being viewed by others

References

  1. C Cellier B Landi A Faye P Wind P Frileux P-H Cugnenc J-P Barbier (1996) ArticleTitleUpper gastrointestinal tract fistulae: endoscopic obliteration with fibrin sealant Gastrointest Endosc 44 731–733 Occurrence Handle1:STN:280:ByiC3szmslc%3D Occurrence Handle8979068

    CAS  PubMed  Google Scholar 

  2. J-M Dumonceau M Cremer B Lalmand J Devière (1999) ArticleTitleEsophageal fistula sealing: choice of stent, practical management, and cost Gastrointest Endosc 49 70–78 Occurrence Handle1:STN:280:DyaK1M%2FovVSjsw%3D%3D Occurrence Handle9869726

    CAS  PubMed  Google Scholar 

  3. H Groitl T Horbach (1996) ArticleTitleEndoscopic treatment of anastomosis insufficiency perforation in the esophagus with fibrin glue Langenbecks Arch Chir Suppl Kongressbd 113 753–754 Occurrence Handle1:STN:280:ByiB3Mvit1M%3D Occurrence Handle9101981

    CAS  PubMed  Google Scholar 

  4. W-Y Lau K-L Leung K-H Kwong IC Davey C Robertson JJW Dawson SCS Cung AKC Li (1996) ArticleTitleA randomised study comparing laparoscopic versus open repair of perforated peptic ulcer using suture or sutureless technique Ann Surg 224 131–138 Occurrence Handle10.1097/00000658-199608000-00004 Occurrence Handle1:STN:280:BymA3srgsV0%3D Occurrence Handle8757375

    Article  CAS  PubMed  Google Scholar 

  5. MB Orringer (1991) Complications of esophageal resection and reconstruction JA Waldhausen MB Orringer (Eds) Complications in cardiothoracic surgery Mosby Year Book St. Louis 354–369

    Google Scholar 

  6. M Pross T Manger I Mirow H Lippert (1999) ArticleTitleDie Therapieoptionen postoperativer Fisteln am oberen Gastrointestinaltrakt Zentralbl Chir 124 IssueIDSuppl 2 45–46

    Google Scholar 

  7. M Pross T Manger T Reinheckel L Mirow D Kunz H Lippert (2000) ArticleTitleEndoscopic treatment of clinically symptomatic leaks of thoracic esophageal anastomoses Gastrointest Endosc 51 73–76 Occurrence Handle1:STN:280:DC%2BD3c%2Fpt1yjsQ%3D%3D Occurrence Handle10625803

    CAS  PubMed  Google Scholar 

  8. A Segalin L Bonavina M Lazzerini F Ruberto ParticleDe C Faranda A Peracchia (1996) ArticleTitleEndoscopic management of inveterate esophageal perforations and leaks Surg Endosc 10 928–932 Occurrence Handle10.1007/s004649900200 Occurrence Handle1:STN:280:ByiC2cjptFU%3D Occurrence Handle8703154

    Article  CAS  PubMed  Google Scholar 

  9. M Torre G Chiesa M Ravini M Vercelloni PA Belloni (1994) ArticleTitleEndoscopic gluing of bronchopleural fistula Ann Thorac Surg 58 901–902 Occurrence Handle1:STN:280:ByqD3s7kt1E%3D Occurrence Handle7944733

    CAS  PubMed  Google Scholar 

  10. JD Urschel (1995) ArticleTitleEsophagogastrostomy anastomotic leaks complicating esophagectomy: a review Am J Surg 169 634–640 Occurrence Handle10.1016/S0002-9610(99)80238-4 Occurrence Handle1:STN:280:ByqB1cbls1I%3D Occurrence Handle7771633

    Article  CAS  PubMed  Google Scholar 

  11. IE Willetts NE Dudley PKH Tam (1998) ArticleTitleEndoscopic treatment of recurrent tracheo-oesophageal fistulae: long-term results Pediatr Surg Int 13 256–258 Occurrence Handle10.1007/s003830050310 Occurrence Handle1:STN:280:DyaK1c3itFanuw%3D%3D Occurrence Handle9553183

    Article  CAS  PubMed  Google Scholar 

  12. O Zmora N Mizrahi N Rotholtz AJ Pikarsky EG Weiss JJ Nogueras SD Wexner (2003) ArticleTitleFibrin glue sealing in the treatment of perineal fistulas Dis Colon Rectum 46 584–589 Occurrence Handle12792432

    PubMed  Google Scholar 

Download references

Acknowledgments.

S. Truong and G. Böhm have equally contributed to the article. The authors would like to dedicate this article to V. Schumpelick on the occasion of his 60th birthday.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to G. Böhm.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Truong, S., Böhm, G., Klinge, U. et al. Results after endoscopic treatment of postoperative upper gastrointestinal fistulas and leaks using combined Vicryl plug and fibrin glue. Surg Endosc 18, 1105–1108 (2004). https://doi.org/10.1007/s00464-003-8286-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00464-003-8286-7

Keywords

Navigation