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Power spectral analysis of heart rate variability during positive pressure pneumoperitoneum

The significance of increased cardiac sympathetic expression

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Abstract

Background

Positive pressure pneumoperitoneum (PPP) effects on the autonomic nervous system (ANS) might be of clinical importance, as imbalance in the autonomic cardiac control might lead to serious consequences.

Methods

Fifteen healthy patients undergoing elective laparoscopic cholecystectomy were analyzed for cardiac autonomic nervous activity by spectral heart rate variability, during awake state, before and after intubation, during CO2 PPP (14 mmHg), and after CO2 evacuation. The very low, low, high and very high frequency (VLF, LF, HF, VHF respectively) bands of the spectral density of the heart rate variability (HRV) and their normalized values, as well as the LF/HF ratio, were obtained from the power spectra of R-R intervals, using the fast-Fourier transformation algorithm.

Results

Using Friedman’s nonparametric test, only the difference between the power of LF during anesthesia (median 30.74) and the middle of PPP (median 195.66) was found to be significant (p<0.012). Such change was recorded in 14 patients (p=0.001, sign test).

Conclusions

Increased LF power reflects sympathetic cardiac activation. As the LF range accounts for regulation of blood pressure and baroreflex, several mechanisms may explain this activation. This in turn may predispose patients who suffer from cardiac disease to higher risk of developing ventricular arrhythmias, besides the possible adverse hemodynamic consequences of PPP.

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Authors and Affiliations

  1. Department of Surgery, Western Galilee Hospital, Nahariya, Israel

    A. Bickel & A. Eitan

  2. Department of Cardiology, Western Galilee Hospital, Nahariya, Israel

    M. Yahalom, N. Roguin & J. Breslava

  3. Department of Anesthesiology, Western Galilee Hospital, Nahariya, Israel

    R. Frankel & S. Ivry

  4. Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel

    A. Bickel, M. Yahalom, N. Roguin, R. Frankel, J. Breslava, S. Ivry & A. Eitan

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  1. A. Bickel
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  2. M. Yahalom
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  3. N. Roguin
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  4. R. Frankel
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  5. J. Breslava
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Online publication: 3 May 2002

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Bickel, A., Yahalom, M., Roguin, N. et al. Power spectral analysis of heart rate variability during positive pressure pneumoperitoneum. Surg Endosc 16, 1341–1344 (2002). https://doi.org/10.1007/s00464-001-9211-6

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  • DOI: https://doi.org/10.1007/s00464-001-9211-6

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