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Rotating simplex method of optimization of physical parameters for higher production of extracellular pectinases in bioreactor

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Abstract

Rotating simplex method of optimization has been successfully used to determine the optimal conditions for extracellular pectinase production by Aspergillus niger in batch bioreactor. Maximum production of 1.132 U of polymethylgalacturonase, 1.313 U of polygalacturonase and 0.0091 U of pectinlyase was obtained at pH (controlled). 3.38; agitation rate, 483 rpm and aeration rate, 2.12 vvm. These conditions were found to be more suitable for pectinase production.

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Authors and Affiliations

  1. Biotechnology Research Centre, Indian Institute of Technology-Madras, Chennai – 600 036, India, , , , , , IN

    T. Panda & G. S. N. Naidu

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  1. T. Panda
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  2. G. S. N. Naidu
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Received: 21 June 1999

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Panda, T., Naidu, G. Rotating simplex method of optimization of physical parameters for higher production of extracellular pectinases in bioreactor. Bioprocess Engineering 23, 47–49 (2000). https://doi.org/10.1007/s004499900119

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  • DOI: https://doi.org/10.1007/s004499900119

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