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Impact of Hardy–Weinberg disequilibrium on post-imputation quality control

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Acknowledgments

The contents of this publication are solely the responsibility of the author and do not necessarily represent the official view of the National Institutes of Health. The Howard University Family Study was supported by National Institutes of Health grants S06GM008016-320107 to Charles N. Rotimi and S06GM008016-380111 to Adebowale Adeyemo. Participant enrollment was carried out at the Howard University General Clinical Research Center, supported by National Institutes of Health grant 2M01RR010284. Genotyping support was provided by the Coriell Institute for Medical Research. This research was supported by the Intramural Research Program of the Center for Research on Genomics and Global Health (CRGGH). The CRGGH is supported by the National Human Genome Research Institute, the National Institute of Diabetes and Digestive and Kidney Diseases, the Center for Information Technology, and the Office of the Director at the National Institutes of Health (Z01HG200362). I thank Adebowale Adeyemo and two anonymous reviewers for their helpful comments.

Conflict of interest

The author declares no conflicts of interest.

Ethical standard

Ethics approval for the Howard University Family Study was obtained from the Howard University Institutional Review Board and written informed consent was obtained from each participant. All clinical investigation was conducted according to the principles expressed in the Declaration of Helsinki.

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  1. Center for Research on Genomics and Global Health, National Human Genome Research Institute, Building 12A, Room 4047, 12 South Dr., MSC 5635, Bethesda, MD, 20892-5635, USA

    Daniel Shriner

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  1. Daniel Shriner
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Correspondence to Daniel Shriner.

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Shriner, D. Impact of Hardy–Weinberg disequilibrium on post-imputation quality control. Hum Genet 132, 1073–1075 (2013). https://doi.org/10.1007/s00439-013-1336-x

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  • DOI: https://doi.org/10.1007/s00439-013-1336-x

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