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A human case of subcutaneous dirofilariasis caused by Dirofilaria repens in Vietnam: histologic and molecular confirmation

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Abstract

Human dirofilariasis caused by infection with Dirofilaria worms has been frequently reported. The symptoms associated with infection by these filarial parasites, which are transmitted to humans by zooanthropophilic mosquitoes, are characterized by mainly pulmonary and subcutaneous nodules. Here, we report the first case in Vietnam of a subcutaneous dirofilariasis with a painful nodule in the right eyelid. An immature female worm was removed by excisional biopsy and identified as Dirofilaria repens by histology and DNA analysis.

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Acknowledgements

This work was conducted as part of a core university program between Vietnam and Japan sponsored by the Japan Society for Promotion of Sciences. This work was also supported in part by a grant-in-aid from the Ministry of Health, Labour, and Welfare, Japan (H20-Shinko-Ippan-016).

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Correspondence to Thi Cam Thach Dang.

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Nucleotide sequence data reported in the present paper are deposited in the DDBJ/GenBank/EMBL databases under the accession numbers AB547465 and AB547466 for the cytochrome c oxidase subunit 1 and 12S rRNA genes, respectively.

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Dang, T.C.T., Nguyen, T.H., Do, T.D. et al. A human case of subcutaneous dirofilariasis caused by Dirofilaria repens in Vietnam: histologic and molecular confirmation. Parasitol Res 107, 1003–1007 (2010). https://doi.org/10.1007/s00436-010-1961-4

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  • DOI: https://doi.org/10.1007/s00436-010-1961-4

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