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Genotyping of Panamanian Trypanosoma cruzi stocks using the calmodulin 3′UTR polymorphisms

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Abstract

Mutations in the 3′ untranslated region of calmodulin gene have recently been reported to be specific to different Trypanosoma cruzi lineages. In the present report, this molecular marker was used to genotype 24 T. cruzi isolates from humans and vectors from different endemic areas in Panama. The finding of solely T. cruzi I genotype might explain the low morbidity of Chagas’ disease in the region when compared to other countries in Latin America.

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Acknowledgements

This study was partially funded by the International Atomic Energy Agency, grant PAN 6010.

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Authors and Affiliations

  1. Center for Research and Diagnosis of Parasitic Diseases, Faculty of Medicine, University of Panama, Panama, Panama

    Octavio E. Sousa

  2. Instituto Conmemorativo Gorgas de Estudios de la Salud, Panama, Panama

    Franklyn Samudio, Jose E. Calzada & Octavio E. Sousa

  3. Oswaldo Cruz Institute, Fiocruz, Rio de Janiero, Brazil

    Adeilton Brandao & Octavio Fernandes

Authors
  1. Adeilton Brandao
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  2. Franklyn Samudio
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  3. Octavio Fernandes
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  4. Jose E. Calzada
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  5. Octavio E. Sousa
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Correspondence to Octavio E. Sousa.

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Brandao, A., Samudio, F., Fernandes, O. et al. Genotyping of Panamanian Trypanosoma cruzi stocks using the calmodulin 3′UTR polymorphisms. Parasitol Res 102, 523–526 (2008). https://doi.org/10.1007/s00436-007-0775-5

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  • DOI: https://doi.org/10.1007/s00436-007-0775-5

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