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A case report of sporadic hemiplegic migraine associated cerebral hypoperfusion: comparison of arterial spin labeling and dynamic susceptibility contrast perfusion MR imaging

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Abstract

The pathogenesis of sporadic hemiplegic migraine remains unclear, and perfusion-weighted magnetic resonance imaging (PWI) has been used for characterization of hemodynamic changes in migraine aura. We report a case of sporadic hemiplegic migraine in which magnetic resonance perfusion imaging showed left cerebral hypoperfusion. Dynamic susceptibility contrast (DSC) perfusion maps showed hypoperfusion with posterior predominance in the left cerebral hemisphere. Findings with arterial spin labeling (ASL) perfusion correlated well with DSC perfusion findings.

Conclusion: With unique advantages compared with DSC PWI, ASL has significant potential in the evaluation of the patients with sporadic hemiplegic migraine.

What is Known:

• Sporadic hemiplegic migraine is a rare variety of migraine defined by migraine attacks, which include the presence of motor weakness/hemiparesis during the aura phase and where no first- or second-degree relative (parent, sibling, or child) has identical attacks.

What is New:

• Reports on imaging abnormalities described in sporadic hemiplegic migraine are sparse.

• To our knowledge, this is the first report to describe arterial spin labeling (ASL) perfusion abnormalities in patients with sporadic hemiplegic migraine, as compared with dynamic susceptibility contrast perfusion-weighted magnetic resonance imaging (PWI).

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Abbreviations

ASL:

Arterial spin labeling

CBF:

Cerebral blood flow

DSC:

Dynamic susceptibility contrast

PWI:

Perfusion-weighted magnetic resonance imaging

Tmax:

Time-to max

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Conflict of interest

The authors declare that they have no (financial) conflict of interest.

Ethical approval

The case report was approved by the local ethical committee.

Informed consent

The requirement of informed consent was waived for this retrospective study.

Source of support

No sources of financial and material support to be declared.

Author’s contributions

SH Kim and MJ Kang contributed in the conception, analysis, and interpretation of the study. SS Choi drafted the manuscript for important intellectual content.

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Authors and Affiliations

  1. Department of Radiology, Dong-A University Medical Center, 1,3-ga, Dongdaeshin-dong, Seo-gu, Busan, 602-715, South Korea

    Sanghyeon Kim, Myongjin Kang & Sunseob Choi

Authors
  1. Sanghyeon Kim
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  2. Myongjin Kang
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  3. Sunseob Choi
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Corresponding author

Correspondence to Myongjin Kang.

Additional information

Communicated by Mario Bianchetti

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Kim, S., Kang, M. & Choi, S. A case report of sporadic hemiplegic migraine associated cerebral hypoperfusion: comparison of arterial spin labeling and dynamic susceptibility contrast perfusion MR imaging. Eur J Pediatr 175, 295–298 (2016). https://doi.org/10.1007/s00431-015-2609-2

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  • DOI: https://doi.org/10.1007/s00431-015-2609-2

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