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Cushing’s syndrome and adrenal insufficiency after intradermal triamcinolone acetonide for keloid scars

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Abstract

A 6-year-old girl was admitted to our hospital for excessive weight gain. On presentation, she had a typical Cushingoid appearance and hypertension. Laboratory analysis was indicative for an exogenous glucocorticoid source, showing values that were low for serum cortisol and adrenocorticotropin and for 24-h urinary glucocorticoid (metabolite) excretion. Five and 2 months before presentation, she was treated with intradermal triamcinolone acetonide for keloid scars. Recovery of intrinsic cortisol production occurred 12 months after the last steroid dose. Intradermal triamcinolone acetonide for keloid scars in children should be used with care taking into account the here reported complication.

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Authors and Affiliations

  1. Department of Pediatrics, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands

    Martijn J. J. Finken & Dick Mul

  2. Department of Pediatrics, VU Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, The Netherlands

    Martijn J. J. Finken

  3. Department of Pediatrics, Haga Teaching Hospital/Juliana Children’s Hospital, Sportlaan 600, 2566 MJ, Den Haag, The Netherlands

    Dick Mul

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  1. Martijn J. J. Finken
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Correspondence to Martijn J. J. Finken.

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Finken, M.J.J., Mul, D. Cushing’s syndrome and adrenal insufficiency after intradermal triamcinolone acetonide for keloid scars. Eur J Pediatr 169, 1147–1149 (2010). https://doi.org/10.1007/s00431-010-1165-z

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  • DOI: https://doi.org/10.1007/s00431-010-1165-z

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