Abstract
The aims of this study were to assess the incidence and risk factors of major central venous catheter (CVC)-related complications in a large cohort of children affected by oncological, hematological, or immunological diseases in a 7-year prospective observational study at a single center. Nine hundred fifteen CVCs were inserted in 748 children for a total period of 307,846 CVC-days. Overall, 298 complications were documented with a complication rate of 0.97/1,000 CVC-days: 105 mechanical complications (dislocations 0.30/1,000 CVC-days, ruptures 0.04/1,000 CVC-days), 174 infections (bloodstream infections 0.46/1,000 CVC-days, tunnel infections 0.10/1,000 CVC-days), and 19 thrombosis (0.06/1,000 CVC-days). Significant risk factors were: diagnosis of acute lymphoblastic leukemia (ALL) and age ≤3 years for dislocations; nonmalignant disease for ruptures; ALL for thrombosis; double-lumen and partially implanted CVCs for bloodstream infections; age ≤3 years for tunnel infections. In conclusion, the rate of CVC-related complications in children was lower than that usually reported.
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Acknowledgements
We are grateful to the doctors of the Department of Cardiac Surgery and Cardiology Service, Regina Margherita Children’s Hospital for the surgical collaboration and to our department’s nursing staff for their dedication in taking care of the patients. We are also grateful to Mr. Andrew Martin Garvey for patiently revising our paper.
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Pinon, M., Bezzio, S., Tovo, P.A. et al. A prospective 7-year survey on central venous catheter-related complications at a single pediatric hospital. Eur J Pediatr 168, 1505–1512 (2009). https://doi.org/10.1007/s00431-009-0968-2
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DOI: https://doi.org/10.1007/s00431-009-0968-2