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Osteoporosis in juvenile idiopathic arthritis- a practical approach to diagnosis and therapy

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Abstract

In all subgroups of juvenile idiopathic arthritis, a decrease in bone mass has been described in a high percentage of children. Recently, new pathogenetic concepts have identified muscle mass as the strongest predictor of bone mass and bone is now recognized as part of the musculoskeletal system. In addition, the sophisticated use of bone densitometry in pediatrics, including new measurement techniques, has provided the tools for a reliable assessment. A standardized diagnostic approach to the musculoskeletal system, including prophylaxis and therapy, is, therefore, mandatory in all children with JIA who do not achieve rapid remission. In this review, diagnostic and therapeutic options are being described and possibilities to incorporate them into clinical practice are suggested.

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Authors and Affiliations

  1. Department of Pediatric Pneumology and Immunology, Charite University Medicine, Berlin, Germany

    Johannes Roth

  2. Children’s Hospital University of Munich, Munich, Germany

    Susanne Bechtold

  3. Department of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany

    Gudrun Borte

  4. Children’s Hospital MHH, Hannover, Germany

    Frank Dressler

  5. University Children’s Hospital, Wuerzburg, Germany

    Hermann J. Girschick

  6. Municipal Hospital, “St. Georg” Leipzig, Children’s Hospital, Leipzig, Germany

    Michael Borte

  7. SPZ Rheumatology, Charite Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany

    Johannes Roth

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  1. Johannes Roth
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Correspondence to Johannes Roth.

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Roth, J., Bechtold, S., Borte, G. et al. Osteoporosis in juvenile idiopathic arthritis- a practical approach to diagnosis and therapy. Eur J Pediatr 166, 775–784 (2007). https://doi.org/10.1007/s00431-007-0484-1

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  • DOI: https://doi.org/10.1007/s00431-007-0484-1

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