Skip to main content
SpringerLink
Log in

Subacute cardiotoxicity caused by anthracycline therapy in children: can dexrazoxane prevent this effect?

  • Short Report
  • Published:
European Journal of Pediatrics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Cvetkovic RS, Scott L (2005) Dexrazoxane: a review of its use for cardioprotection during anthracycline chemotherapy. Drugs 65:1005–1024, 2005

    Article  PubMed  CAS  Google Scholar 

  2. Elbl L, Hrstkova H, Tomaskova I, Blazek B, Michalek J (2005) Long-term serial echocardiographic examination of late anthracycline toxicity and its prevention by dexrazoxane in paediatric patients. Eur J Pediatr 164:678–684

    Article  PubMed  Google Scholar 

  3. Greiner MA, Lipschultz SE (1998) Epidemiology of anthracycline cardiotoxicity in children and adults. Seminar Oncol 25[uppl 10]:72–85

    Google Scholar 

  4. Kremer LCM, Van Dalen EC, Offriga M, Ottenkamp J, Voute PA (2001) Anthracycline induced clinical heart failure in a cohort of 607 children: long-term follow-up study. J Clin Oncol 19:191–196

    PubMed  CAS  Google Scholar 

  5. Lipschultz SE (2006) Exposure to anthracyclines during childhood causes cardiac injury. Semin Oncol 33[S8]:8–14

    Article  Google Scholar 

  6. Wouters KA, Kremer LC, Miller TL, Herman EH, Lipschultz SE (2005) Protecting against antracycline-induced myocardial damage: a review of the most promising strategies. Br J Haematol 131:561–578

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgements

The study was supported by the Hungarian Research Foundation (OTKA TO-42500). The authors appreciate the assistance of Dr. Miklos Garami and Peter Hauser in presenting some additional data.

Author information

Authors and Affiliations

  1. Haemato-oncology Division, 2nd Department of Pediatrics, Semmelweis University, Tuzolto 7-9., 1094, Budapest, Hungary

    Gábor T. Kovács, Hajna Erlaky, Kornélia Tóth, Judit Szabolcs, Monika Csóka, László Jókúti, Dániel Erdélyi & Judit Müller

  2. First Department of Pediatrics, Semmelweis University, Budapest, Hungary

    Erzsébet Horváth

Authors
  1. Gábor T. Kovács
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hajna Erlaky
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kornélia Tóth
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Erzsébet Horváth
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Judit Szabolcs
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Monika Csóka
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. László Jókúti
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Dániel Erdélyi
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Judit Müller
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Gábor T. Kovács.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kovács, G.T., Erlaky, H., Tóth, K. et al. Subacute cardiotoxicity caused by anthracycline therapy in children: can dexrazoxane prevent this effect?. Eur J Pediatr 166, 1187–1188 (2007). https://doi.org/10.1007/s00431-006-0370-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00431-006-0370-2

Keywords

Search

Navigation