Abstract.
The neuraminidase inhibitors signifies a breakthrough in the treatment of influenza. We compared the outcomes of influenza in 56 patients treated with zanamivir or oseltamivir to a group of 52 influenza patients from the time before these drugs were available. The duration of illness was reduced by 45%, the severity of symptoms by 40% and the administration of antibiotics by 32%. The data from this small group of patients of our ambulatory practice correspond to the results of large randomized placebo-controlled double-blind studies on zanamivir and oseltamivir. Our clinical observations and painful experiences have taught us to take every case of suspected influenza seriously. Since considerable influenza-related complications are common even in otherwise healthy individuals, patients should immediately consult their doctor when an illness with sudden onset of fever and cough or another respiratory symptom occur.
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Vogel, G.E. Neuraminidase inhibitors in the management of influenza – experience of an outpatient practice. Med Microbiol Immunol 191, 161–163 (2002). https://doi.org/10.1007/s00430-002-0138-x
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DOI: https://doi.org/10.1007/s00430-002-0138-x