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Right insula for our sense of limb ownership and self-awareness of actions

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Abstract

Normally, we are aware that our arms and legs belong to us and not to someone else. However, some stroke patients with hemiparesis/-plegia after right-sided stroke show a disturbed sensation of limb ownership and a disturbed self-awareness of actions and such patients with anosognosia for hemiparesis/plegia typically deny their paresis/-plegia and are convinced that their limbs function normally. They may experience their limb(s) as not belonging to them and may even attribute them to other persons. Modern lesion analyses techniques in such patients and recent neuroimaging results in healthy subjects suggest a prominent role of the right insula for our sense of limb ownership as well as for our feeling of being involved in a movement—our sense of agency. We thus hypothesize that the right insular cortex constitutes a central node of a network involved in human body scheme representation.

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Acknowledgments

This work was supported by the Bundesministerium für Bildung und Forschung (BMBF-Verbundprojekt “Räumliche Orientierung” 01GW0641) and the Deutsche Forschungsgemeinschaft (KA 1258/10-1).

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  1. Section of Neuropsychology, Center of Neurology, Hertie-Institute for Clinical Brain Research, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany

    Hans-Otto Karnath

  2. Department of Neurology, University of Mainz, Mainz, Germany

    Bernhard Baier

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  1. Hans-Otto Karnath
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Correspondence to Hans-Otto Karnath.

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Karnath, HO., Baier, B. Right insula for our sense of limb ownership and self-awareness of actions. Brain Struct Funct 214, 411–417 (2010). https://doi.org/10.1007/s00429-010-0250-4

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