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A volumetric study of the corpus callosum in 20s and 40s Korean people

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Abstract

The purpose of this study was to measure the average corpus callosum volume of normal Koreans (aged in their 20s or 40s) and to analyze the effects of gender, age, and body parameters, such as height and weight on corpus callosum size. Magnetic resonance brain images were recorded for 68 people in their 20s (29 men, 39 women) and 91 in their 40s (36 men, 55 women). Intracranial volume was calculated using cerebral size and corpus callosum volume was normalized by covariance method. To investigate the effect of gender and age on corpus callosum volume, two-way analysis of variance, which used gender (two levels) and age (two levels) as independent variables, was employed. Multiple regression analysis was carried out to investigate the effect of body parameters, such as height and weight, according to the age and gender on the changes in corpus callosum volume. The average corpus callosum volume of Korean men (11.09 cm3) was larger than that of Korean women (9.61 cm3). There was no significant difference in corpus callosum volume between 20s (10.43 cm3) and 40s (10.12 cm3). There was a positive relationship between body weight and corpus callosum volume for 20s, but not for 40s.

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Acknowledgments

This work was supported by the Second-Phase of BK (Brain Korea) 21 Project in 2007.

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Authors and Affiliations

  1. Department of Anatomy, School of Medicine, Konkuk University, Seoul, South Korea

    Beob-Yi Lee

  2. Department of Psychology, Institute for Brain Research, Chungnam National University, Daejon, South Korea

    Jin-Hun Sohn

  3. Department of Biomedical Engineering, Research Institute of Biomedical Engineering, College of Biomedical and Health Science, Konkuk University, 322 Danwall-dong, Chungju, Chungbuk, 380-701, South Korea

    Mi-Hyun Choi, Su-Jeong Lee, Hyo-Seong Kim, Jae-Woong Yang, Jin-Seung Choi, Hyung-Sik Kim, Jeong-Han Yi, Gye-Rae Tack & Soon-Cheol Chung

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  1. Beob-Yi Lee
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Correspondence to Soon-Cheol Chung.

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Lee, BY., Sohn, JH., Choi, MH. et al. A volumetric study of the corpus callosum in 20s and 40s Korean people. Brain Struct Funct 213, 463–467 (2009). https://doi.org/10.1007/s00429-009-0209-5

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  • DOI: https://doi.org/10.1007/s00429-009-0209-5

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