Abstract
A 57-year-old male patient presented with a cystic lesion in the tail of the pancreas, which was considered to be a pseudocyst. He was treated by cystojejunostomy but one year later a tumour was found to have invaded the stomach and jejunum. This was an osteoclast-like giant cell tumour containing a small area of typical ductal adenocarcinoma. Immunohistochemical staining revealed that the pleomorphic tumour cells were positive for cytokeratin, epithelial membrane antigen, vimentin and the proliferation marker MIB-1. The osteoclast-like giant cells and some small histiocytic cells stained for leukocyte common antigen and histiocytic markers and were negative for MIB-1. At autopsy, tumour rests were found in the pancreas but there were no metastases. Osteoclast-like giant cell tumours of the pancreas may present as cystic lesions and should be included in the differential diagnosis of pseudocysts.
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Received: 19 December 1996 / Accepted: 20 March 1997
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Oehler, U., Jürs, M., Klöppel, G. et al. Osteoclast-like giant cell tumour of the pancreas presenting as a pseudocyst-like lesion. Virchows Archiv 431, 215–218 (1997). https://doi.org/10.1007/s004280050091
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DOI: https://doi.org/10.1007/s004280050091