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Thyroid-like follicular carcinoma of the kidney: report of two cases with detailed immunohistochemical profile and literature review

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Abstract

Thyroid-like follicular carcinoma of the kidney (TLFC) is an unusual histological variant of renal cell carcinoma not included in the current WHO classification of renal tumors. Its morphological features resemble a large spectrum of benign and malignant renal and extra-renal conditions which should be ruled out in the diagnostic process. Because TLFC outcome is different from the other variants of renal cell carcinoma, the exploration for disease-specific markers is mandatory. The aim of the present paper is to illustrate the histological characteristics and immunohistochemical profile of two new cases along with a brief review of the literature.

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Acknowledgments

The authors thank Dr. P.R. Valentini for her invaluable technical assistance.

Conflict of interest

The authors have no conflict of interest to declare.

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Authors and Affiliations

  1. Department of Medicine, Surgical Pathology and Cytopathology Unit, University Hospital of Padua, Via Aristide Gabelli, 61-35121, Padua (PD), Italy

    Lara Alessandrini, Matteo Fassan & Marina Paola Gardiman

  2. Department of Surgical Oncology and Gastroenterology Sciences, General Oncology Unit, University of Padua, Padua (PD), Italy

    Matteo Fassan

  3. Department of Surgical Oncology and Gastroenterology Sciences, Urology Unit, University of Padua, Padua (PD), Italy

    Andrea Guttilla, Fabio Zattoni, Tommaso Prayer Galletti & Filiberto Zattoni

Authors
  1. Lara Alessandrini
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  2. Matteo Fassan
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  3. Marina Paola Gardiman
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  4. Andrea Guttilla
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  5. Fabio Zattoni
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  6. Tommaso Prayer Galletti
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  7. Filiberto Zattoni
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Correspondence to Marina Paola Gardiman.

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Alessandrini, L., Fassan, M., Gardiman, M.P. et al. Thyroid-like follicular carcinoma of the kidney: report of two cases with detailed immunohistochemical profile and literature review. Virchows Arch 461, 345–350 (2012). https://doi.org/10.1007/s00428-012-1298-8

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  • DOI: https://doi.org/10.1007/s00428-012-1298-8

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