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Dedifferentiated liposarcoma of the oral cavity with angiosarcomatous dedifferentiation

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Abstract

We report a unique case of a 42-year-old woman with a dedifferentiated liposarcoma of the soft tissue of the oral cavity with angiosarcomatous dedifferentiation. Liposarcomas compromising the head and neck region are very unusual, and most of the cases in oral cavity show a well-differentiated pattern. Dedifferentiation in liposarcomas occurs in about 10% of the cases and, when it occurs, the dedifferentiated areas usually resemble high-grade fibrosarcoma or pleomorphic sarcoma. Divergent differentiation might also occur. To the best of our knowledge, there are only nine cases of dedifferentiated liposarcoma of the oral cavity, none of which show an angiosarcomatous dedifferentiation.

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Acknowledgements

We thank Juliana and Andrew Jernigan for the english review.

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Authors and Affiliations

  1. Department of Pathology, Centro de Tratamento e Pesquisa, Hospital do Câncer, A. C. Camargo, R. Prof Antônio Prudente 211, Liberdade, 01509-900, São Paulo, Brazil

    Isabela Werneck da Cunha & Fernando Augusto Soares

  2. Department of Head and Neck Surgery, Centro de Tratamento e Pesquisa, Hospital do Câncer, A. C. Camargo, São Paulo, Brazil

    Luiz Paulo Kowalski

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  1. Isabela Werneck da Cunha
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  2. Luiz Paulo Kowalski
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  3. Fernando Augusto Soares
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Correspondence to Isabela Werneck da Cunha.

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da Cunha, I.W., Kowalski, L.P. & Soares, F.A. Dedifferentiated liposarcoma of the oral cavity with angiosarcomatous dedifferentiation. Virchows Arch 446, 456–459 (2005). https://doi.org/10.1007/s00428-005-1207-5

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  • DOI: https://doi.org/10.1007/s00428-005-1207-5

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