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Auxin dynamics: the dazzling complexity of a small molecule’s message

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Abstract

The phytohormone auxin is a potent regulator of plant development. Since its discovery in the beginning of the twentieth century many aspects of auxin biology have been extensively studied, ranging from biosynthesis and metabolism to the elucidation of molecular components of downstream signaling. With the identification of the F-box protein TIR1 as an auxin receptor a major breakthrough in understanding auxin signaling has been achieved and recent modeling approaches have shed light on the putative mechanisms underlying the establishment of auxin gradients and maxima essential for many auxin-regulated processes. Here, we review these and other recent advances in unraveling the entanglement of biosynthesis, polar transport and cellular signaling events that allow small auxinic molecules to facilitate their complex regulatory action.

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Acknowledgments

We are grateful to Bill Gray, Paul Overvoorde, Claus Wasternack and Nadine Schumann for critical comments on the manuscript, and Christine Kaufmann and Annett Kohlberg for assistance with graphics and pictures, respectively. We also thank Joanne Chory and Jose Alonso for sharing unpublished data. Furthermore, we would like to acknowledge two anonymous reviewers for excellent suggestions. Funding in the authors’ lab is provided by the ‘Exzellenzinitiative für Biowissenschaften’ by the Federal State of Sachsen-Anhalt, Germany.

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  1. Independent Junior Research Group, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle/Saale, Germany

    Carolin Delker, Anja Raschke & Marcel Quint

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  1. Carolin Delker
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  2. Anja Raschke
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  3. Marcel Quint
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Correspondence to Marcel Quint.

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Delker, C., Raschke, A. & Quint, M. Auxin dynamics: the dazzling complexity of a small molecule’s message. Planta 227, 929–941 (2008). https://doi.org/10.1007/s00425-008-0710-8

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  • DOI: https://doi.org/10.1007/s00425-008-0710-8

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