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Surgery for liver metastases originating from sarcoma—case series

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Abstract

Introduction

Liver metastases originating from various types of sarcoma are a rare reason for hepatic resection. So far, even multicentre studies do hardly provide statistically relevant sample sizes. Thus, review of available data can provide surgeons with useful information in similar cases. Therefore, this study can be regarded more as a contribution to this pool of data than as a stand-alone paper.

Patients and methods

The study includes 10 women and five men who underwent subtotal hepatic resection for solitary (n = 4) and multiple (n = 11) liver metastases originating from sarcoma. The median tumour diameter was 60 mm (range 20–200 mm).

Results

Morbidity was 33%. One patient died within 30 days after surgery. Resection was complete (R0) in 67%. Median overall survival was 33.6 months, 5-year survival 27%. The use of Pringle manoeuvre was significantly associated with poorer outcome (p = 0.014) and shorter period of recurrence-free survival (p = 0.012). Diameter of liver lesion over 50 mm showed significantly shorter recurrence-free survival (p = 0.042).

Conclusion

Hepatic resection may be beneficial in patients with isolated sarcoma metastasis in the liver.

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Acknowledgements

The authors thank Rene Adam, M.D. and Javier C Lendoire, M.D. for their review of Table 3 and Eugenia Lamont for proofreading the manuscript.

Conflicts of interest

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Authors and Affiliations

  1. Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna, Austria

    Johannes Zacherl, Raimund Jakesz & Thomas Grünberger

  2. Department of Orthopedics, Medical University of Graz, Auenbruggerplatz 6, 8036, Graz, Austria

    Maximilian Zacherl & Gerald Gruber

  3. Division of General Surgery, Department of Surgery, Medical University of Graz, Graz, Austria

    Gerwin A. Bernhardt, Peter Kornprat, Heinz Bacher & Hans-Jörg Mischinger

  4. Department of Orthopedics, Medical University of Vienna, Vienna, Austria

    Reinhard Windhager

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  1. Maximilian Zacherl
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Correspondence to Maximilian Zacherl.

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Zacherl, M., Bernhardt, G.A., Zacherl, J. et al. Surgery for liver metastases originating from sarcoma—case series. Langenbecks Arch Surg 396, 1083–1091 (2011). https://doi.org/10.1007/s00423-011-0821-8

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  • DOI: https://doi.org/10.1007/s00423-011-0821-8

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