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Parkinson’s disease influences the perioperative risk profile in surgery

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Abstract

Background and aims

Aim of this study was to define the perioperative risk profile in surgery of patients suffering from Parkinson’s disease (PD) in order to improve treatment options in these patients.

Materials and methods

Over a period of 13 years, 51 patients suffering from Parkinson’s disease treated in the departments of general, visceral, thoracic, vascular, and trauma surgery were retrospectively compared using matched-pair analysis with 51 controls not affected by PD. Both groups of patients were assessed regarding morbidity and mortality, length of treatment, and rehabilitation.

Results

Surgical patients suffering from Parkinson’s disease showed an increase in risk of morbidity. Postoperative falls occurred more commonly (entire cohort, p < 0.03). In PD patients treated in the trauma surgery department, postoperative falls (p < 0.04), postoperative stay (p < 0.03), and overall duration of treatment (p < 0.02) were significantly longer than in patients without PD. PD patients of the trauma unit could be discharged home less often for ambulantory rehabilitation after in-patient treatment (p < 0.03).

Conclusions

Concomitant Parkinson’s disease is a significant factor of perioperative morbidity in surgical patients, especially of patients treated in the trauma unit. Perioperative morbidity in PD patients may be influenced by early diagnostic and therapeutic measures.

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Authors and Affiliations

  1. Department of Orthopaedics and Trauma Surgery, University Hospital of Bonn Medical Center, Sigmund-Freud-Straße 25, 53105, Bonn, Germany

    Marcus C. Mueller

  2. Department of Surgery, University Hospital of Bonn Medical Center, Sigmund-Freud-Straße 25, 53105, Bonn, Germany

    Ulf Jüptner, Andreas Türler, Andreas Hirner & Jens Standop

  3. Department of Neurology, University Hospital of Bonn Medical Center, Sigmund-Freud-Straße 25, 53105, Bonn, Germany

    Ullrich Wuellner

  4. Department of Anesthesiology and Intensive Care Medicine, University Hospital of Bonn Medical Center, Sigmund-Freud-Straße 25, 53105, Bonn, Germany

    Stefan Wirz

Authors
  1. Marcus C. Mueller
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  2. Ulf Jüptner
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  3. Ullrich Wuellner
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  4. Stefan Wirz
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  5. Andreas Türler
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  6. Andreas Hirner
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  7. Jens Standop
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Corresponding author

Correspondence to Marcus C. Mueller.

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Mueller, M.C., Jüptner, U., Wuellner, U. et al. Parkinson’s disease influences the perioperative risk profile in surgery. Langenbecks Arch Surg 394, 511–515 (2009). https://doi.org/10.1007/s00423-008-0404-5

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  • DOI: https://doi.org/10.1007/s00423-008-0404-5

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