Abstract
The aim of this investigation was firstly, to examine whether a contralateral repeated bout effect is manifested after a single bout of maximal eccentric muscle actions and secondly, to compare the magnitude of any such protection to an ipsilateral control. Sixteen male subjects undertook 45 repetitions of maximal eccentric contractions of the elbow flexors. The ipsilateral group (IL, N = 8) repeated the exercise using the same arm and the contralateral group (CL, N = 8) repeated the exercise using the contralateral arm 14 days later. Serum creatine kinase (CK), muscle soreness, maximal voluntary contraction (MVC) and range of motion (ROM) were significantly attenuated in the repeated bout for IL. CL also showed a significant reduction in the repeated bout for CK, muscle soreness and MVC. Despite the significant attenuation of dependent variables in both groups the magnitude of change was less in CL compared to IL for CK, soreness, MVC and ROM. The findings demonstrate a repeated bout effect in the contralateral limb after a single bout of maximal eccentric exercise; however, the magnitude of protection in the contralateral limb is less than that manifested in the ipsilateral limb. The apparent contralateral repeated bout effect observed in this investigation is thought to be predominantly mediated by neural mechanisms, although further research is required to elucidate this possibility.
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References
Armstrong RB (1990) Initial events in exercise-induced muscular injury. Med Sci Sports Exerc 22:429–435
Baltzopoulos V, Williams JG, Brodie DA (1991) Sources of error in isokinetic dynamometry: effects of visual feedback on maximum torque measurements. J Orthop Sports Phys Ther 13:138–142
Brockett CL, Morgan DL, Proske U (2001) Human hamstring muscles adapt to eccentric exercise by changing optimum length. Med Sci Sports Exerc 33:783–790
Brown SJ, Child RB, Day SH, Donnelly AE (1997) Exercise-induced skeletal muscle damage and adaptation following repeated bouts of eccentric muscle contractions. J Sports Sci 15:215–222
Carroll TJ, Herbert RD, Munn J, Lee M, Gandavia SC (2006) Contralateral effects of unilateral training: evidence and possible mechanisms. J Appl Physiol 101:1514–1522
Chen TC (2003) Effects of a second bout of maximal eccentric exercise on muscle damage and electromyography activity. Eur J Appl Physiol 89:115–121
Clarkson PM, Nosaka K, Braun B (1992) Muscle function after exercise-induced muscle damage and rapid adaptation. Med Sci Sports Exerc 24:512–520
Connolly DAJ, Reed RV, McHugh MP (2002) The repeated bout effect: does evidence for a crossover effect exist? J Sports Sci Med 1:80–86
Eston R, Peters D (1999) Effects of cold water immersion on the symptoms of exercise-induced muscle injury. J Sports Sci 17:231–238
Hortobágyi T, Lambert NJ, Hill JP (1997) Greater cross education following training with muscle lengthening than shortening. Med Sci Sports Exerc 29:107–112
Hortobágyi T, Houmard J, Fraser D, Dudek R, Lambert J, Tracy J (1998) Normal forces and myofibrillar disruption after repeated eccentric exercise. J Appl Physiol 84:492–498
Hortobágyi T, Scott K, Lambert NJ, Hamilton G, Tracy J (1999) Cross education of muscle strength is greater with stimulated than voluntary contractions. Motor Control 3:205–219
Howatson G, van Someren KA (2005) The reproducibility of peak isometric torque and electromyography activity in unfamiliarised subjects using isokinetic dynamometry on repeated days. Isokinet Exerc Sci 13:103–109
Howatson G, Gaze D, van Someren KA (2005) The efficacy of ice massage in the treatment of exercise-induced muscle damage. Scand J Med Sci Sports 15:416–422
Howatson G, van Someren KA Hortobágyi T (2007) Repeated bout effect after maximal eccentric exercise. Int J Sports Med. doi: 10.1055/s-2007-964866
Knitter AE, Panton L, Rathmacher JA, Petersen A, Sharp R (2000) Effects of beta-hydroxy-beta-methylbutyrate on muscle damage after a prolonged run. J Appl Physiol 89:1340–1344
Lanier AB (2003) Use of anti-inflammatory drugs following exercise-induced muscle injury. Sports Med 33:177–185
Lee M, Carroll TJ (2007) Cross education: possible mechanisms for the contralateral effects of unilateral training. Sports Med 37:1–14
Mair J (1999) Tissue release of cardiac markers: from physiology to clinical applications. Clin Chem Lab Med 37:1077–1084
McHugh MP (2003) Recent advances in the understanding of the repeated bout effect against muscle damage from a single bout of eccentric exercise. Scand J Med Sci Sports 13:88–97
McHugh MP, Connolly DAJ, Eston RG, Gleim GW (1999) Exercise-induced muscle damage and potential mechanisms for the repeated bout effect. Sports Med 27:157–170
McHugh MP, Connolly DAJ, Eston RG, Gleim GW (2000) Electromyographic analysis of exercise resulting in symptoms of muscle damage. J Sports Sci 18:163–172
McHugh MP, Connolly DAJ, Eston RG, Gartman EJ, Gleim GW (2001) Electromyographic analysis of repeated bout effect. J Sports Sci 19:163–170
Munn J, Herbert RD, Gandevia SC (2004) Contralateral effects of unilateral resistance training: a meta-analysis. J Appl Physiol 96:1861–1866
Munn J, Herbert RD, Hancock MJ Gandevia SC (2005) Training with unilateral resistance exercise increases contralateral strength. J Appl Physiol 99:1880–1884
Newham DJ, Jones DA, Clarkson PM (1987) Repeated high-force eccentric exercise: effects on muscle pain and damage. J Appl Physiol 63:1381–1386
Nosaka K, Clarkson PM (1995) Muscle damage following repeated bouts of high force eccentric exercise. Med Sci Sports Exerc 27:1263–1269
Nosaka K, Newton M (2002) Differences in the magnitude of damage between maximal and submaximal eccentric loading. J Strength Cond Res 16:202–208
Nosaka K, Sakamoto K, Newton M Sacco P (2001) How long does the protective effect on eccentric exercise-induced muscle damage last? Med Sci Sports Exerc 33:1490–1495
Pizza FX, Koh TJ, McGregor SJ, Brooks SV (2002) Muscle inflammatory cells after passive stretches, isometric contractions, and eccentric contractions. J Appl Physiol 92:1873–1878
Reich TE, Lindstedt SL, LaStayo PC, Pierotti DJ (2000) Is the spring quality of muscle elastic? Am J Physiol Regul Integr Comp Physiol 278:R1661–R1666
Shima N, Ishida K, Katayama K, Morotome Y, Sato Y, Miyamura M (2002) Cross education of muscular strength during unilateral resistance training and detraining. Eur J Appl Physiol 86:287–294
Warren GL, Lowe DA, Armstrong RB (1999) Measurement tools used in the study of eccentric contraction-induced injury. Sports Med 27:43–59
Warren GL, Hermann KM, Ingalls CP, Masselli MR, Armstrong RB (2000) Decreased EMG median frequency during a second bout of eccentric contractions. Med Sci Sports Exerc 32:820–829
Weir JP, Housh DJ, Housh TJ, Weir LL (1995) The effect of unilateral eccentric weight training and detraining on joint angle specificity, cross training, and the bilateral deficit. J Orthop Sports Phys Ther 22:207–215
Zainuddin Z, Newton M, Sacco P, Nosaka K (2005) Effects of massage on delayed-onset muscle soreness, swelling, and recovery of muscle function. J Athlet Train 40:174–180
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Howatson, G., van Someren, K.A. Evidence of a contralateral repeated bout effect after maximal eccentric contractions. Eur J Appl Physiol 101, 207–214 (2007). https://doi.org/10.1007/s00421-007-0489-5
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DOI: https://doi.org/10.1007/s00421-007-0489-5