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Assessment of liver function in two groups of outdoor workers exposed to arsenic

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Abstract

Purpose

To evaluate whether the exposure to arsenic (As) causes alterations of liver enzymes in two groups of outdoor workers.

Methods

Total urinary As and the levels of AST/GOT, ALT/GPT, and GGT were measured on 80 traffic policemen and 50 police drivers. Personal air samples were obtained for assessing the exposure to As on a subgroup of 20 traffic policemen and 20 police drivers.

Results

Mean values of personal exposure to As, urinary As, AST/GOT, and ALT/GPT were significantly higher in traffic policemen than in the police drivers. Multiple linear regression models showed associations between urinary As and airborne As, ALT/GPT and the job variables, and BMI and urinary As.

Conclusions

These findings contribute toward the evaluation of the hepatic effects of exposure to As in the urban workers.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Unit of Occupational Medicine, Department of Anatomy, Histology, Legal Medicine and Orthopedics, University of Rome “Sapienza”, Viale Regina Elena 336, 00161, Rome, Italy

    Teodorico Casale, Maria Valeria Rosati, Manuela Ciarrocca, Ilaria Samperi, Giorgia Andreozzi, Maria Pia Schifano, Assunta Capozzella, Benedetta Pimpinella, Tiziana Caciari & Francesco Tomei

  2. Department of Psychiatric and Psychological Science, University of Rome “Sapienza”, Rome, Italy

    Gianfranco Tomei

Authors
  1. Teodorico Casale
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  2. Maria Valeria Rosati
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  3. Manuela Ciarrocca
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  4. Ilaria Samperi
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  5. Giorgia Andreozzi
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  6. Maria Pia Schifano
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  7. Assunta Capozzella
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  8. Benedetta Pimpinella
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  9. Gianfranco Tomei
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  10. Tiziana Caciari
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  11. Francesco Tomei
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Corresponding author

Correspondence to Teodorico Casale.

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Casale, T., Rosati, M.V., Ciarrocca, M. et al. Assessment of liver function in two groups of outdoor workers exposed to arsenic. Int Arch Occup Environ Health 87, 745–752 (2014). https://doi.org/10.1007/s00420-013-0914-5

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  • DOI: https://doi.org/10.1007/s00420-013-0914-5

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