Abstract
Objective
Mass carbon disulfide (CS2) poisoning was reported at a viscose rayon factory in Korea. We evaluated the association between CS2 poisoning and the prevalence of metabolic syndrome.
Methods
The cases (n = 170) involved CS2-poisoned subjects, who participated in a health examination conducted at a hospital in Korea in 2005. The controls (n = 170) were selected randomly from the participants in the third Korean National Health and Nutrition Examination Survey. Metabolic syndrome was defined as having at least three of following metabolic abnormalities: abdominal obesity, elevated triglyceride, reduced high-density lipoprotein cholesterol, elevated blood pressure, and elevated fasting glucose levels.
Results
After adjusting for covariates (age, gender, education, marital status, alcohol consumption, and smoking), CS2-poisoned subjects had an increased risk of metabolic syndrome (prevalence ratio 1.57, 95% CI 1.25–1.98).
Conclusions
The findings suggest that CS2 poisoning may increase the risk of metabolic syndrome.
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Acknowledgments
This study was supported by the Wonjin Foundation.
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Jhun, HJ., Lee, SY., Yim, SH. et al. Metabolic syndrome in carbon disulfide-poisoned subjects in Korea: does chemical poisoning induce metabolic syndrome?. Int Arch Occup Environ Health 82, 827–832 (2009). https://doi.org/10.1007/s00420-008-0363-8
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DOI: https://doi.org/10.1007/s00420-008-0363-8