Abstract
The effects of smoking on hearing loss within the context of atherosclerosis was assessed, and the statistical interaction of occupational noise evaluated. A cross-sectional study was conducted in 397 Japanese males working at a metal factory, aged 21–66 years, in a periodical health checkup. The following information was obtained: two smoking indices of smoking status and Brinkman index, occupational noise exposures and atherosclerotic risk factors (body mass index, blood pressure, serum cholesterol, hemoglobin A1c, atherosclerosis index). Hearing acuity was measured at 4 kHz using a pure-tone audiometer in a quiet room. Among the total subjects, 55 (13.9%) were identified as having hearing loss at 4 kHz, and 151 (38.0%) were currently exposed to occupational noise. When adjusted for age and occupational noise exposure, odds ratios (95% confidence intervals) of hearing loss were 3.16 (1.04, 9.62) for past smokers and 3.39 (1.05, 11.01) for heavy smokers (Brinkman index >750 cigarettes per day × number of years), compared with never-smokers. Statistical interaction of occupational noise exposure was insignificant with the association between smoking and hearing loss. When including atherosclerotic risk factors in a multiple model, there were no significant associations between hearing loss and either smoking or any other factors (i.e., occupational noise and atherosclerotic factors). Smoking was found to be associated with hearing loss beyond occupational noise exposure, and this association seemed to be masked by atherosclerotic factors, suggesting that the direction of the atherosclerotic effect on the relationship might need to be explored between smoking and hearing impairment.
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References
Cruickshanks KJ, Klein R, Klein BE, et al (1998) Cigarette smoking and hearing loss: the epidemiology of hearing loss study. JAMA 279:1715–1719
Cunningham DR, Vise LK,Jones LA (1983) Influence of cigarette smoking on extra-high-frequency auditory thresholds. Ear Hear 4:162–165
Ibrahim AS, Fatt-Hi AS (1983) Cigarette smoking and hearing loss. Hygie 2:31–33
Resources A (1970) Report of Inter-Society Commission for Heart Disease Resources. Prevention of Cardiovascular Disease. Primary prevention of the atherosclerotic diseases. Circulation 42:A55–A95
Itoh, A, Nakashima T, Arao H et al (2001) Smoking and drinking habits as risk factors for hearing loss in the elderly: epidemiological study of subjects undergoing routine health checks in Aichi, Japan. Public Health 115:192–196
Juergens JL, Bernatz PE (1980) Atherosclerosis of the extremities. In: Juergens JL, Spitell JS, Fairbairn JF (eds) Peripheral vascular disease. W.B. Saunders, Philadelphia
Karlsmose B, Lauritzen T, Engberg M et al (2000) A five-year longitudinal study of hearing in a Danish rural population aged 31–50 years. Br J Audiol 34:47–55
Kirikae I, Tozuka M, Okamoto S et al (1974) Hearing test (CHOUKAKUKENSAHOU) (in Japanese). Igakushoin, Tokyo
Kleinbaum DG, Kupper LL, Mulller KE, Nizam A (1998) Applied regression analysis and other multivariable methods, 3rd edn. Duxbury, Pacific Grove
Kubo K, Eda S, Yamamoto H, Fujimoto K et al (1999) Expiratory and inspiratory chest computed tomography and pulmonary function tests in cigarette smokers. Eur Respir J 13:252–256
Labor Standards Office, The Department of Labor (2003) General Guide on Industrial Health (Roudou Eisei no Shiori) (in Japanese). Tokyo, Japan Industrial Safety and Health Association
Levine PH (1973) An acute effect of cigarette smoking on platelet function. A possible link between smoking and arterial thrombosis. Circulation 48:619–623
Makishima K (1978) Arteriolar sclerosis as a cause of presbycusis. Otolaryngology 86:ORL322–326
Manninen O (1985) Cardiovascular changes and hearing threshold shifts in men under complex exposures to noise, whole body vibrations, temperatures and competition-type psychic load. Int Arch Occup Environ Health 56:521–574
Minami H, Yoshimura M, Matsuoka H, et al (2001) Lung cancer treated surgically in patients <50 years of age. Chest 120:32–36
Mizoue T, Miyamoto T, Shimizu T (2003) Combined effect of smoking and occupational exposure to noise on hearing loss in steel factory workers. Occup Environ Med 60:56–59
Nakanishi N, Okamoto M, Nakamura K et al (2000) Cigarette smoking and risk for hearing impairment: a longitudinal study in Japanese male office workers. J Occup Environ Med 42:1045–1049
Nomura K (2003) Chapter II-4: auditory screening test (dai 4 shou chouryokukensa) (in Japanese). In: Yano E, Kobayashi K, Yamaoka K (eds) EBM health checkups. Igakushoin, Tokyo
Nomura K (2003) Effects of smoking on the relationship between age and hearing impairment: cross sectional study in Japanese workers who were not exposed to noise (karei no kitsuen to chouryoku heno eikyou: hi souon bakuro sha niokeru oudankenkyuu) (in Japanese). Teikyo Med J 261:23–31
Noorhassim I, Rampal KG (1998) Multiplicative effect of smoking and age on hearing impairment. Am J Otolaryngol 19:240–243
Palmer KT, Griffin MJ, Syddall HE, et al (2004) Cigarette smoking, occupational exposure to noise, and self reported hearing difficulties. Occup Environ Med 61:340–344
Prince MM, Matanoski M (1991) Problems in ascertaining the combined effects of exposures: results of an occupational cohort study of the joint effects of noise and smoking on hearing acuity. In F. D (eds) Proceedings of the 4th international conference on the combined effects of environmental factors. Johns Hopkins University, Baltimore, pp 87–91
Siegelaub AB, Friedman GD, Adour K et al (1974) Hearing loss in adults: relation to age, sex, exposure to loud noise, and cigarette smoking. Arch Environ Health 29:107–109
Talbott E, Helmkamp J, Matthews K et al (1985) Occupational noise exposure, noise-induced hearing loss, and the epidemiology of high blood pressure. Am J Epidemiol 121:501–514
Toppila E, Pyykko I, Starck J (2001) Age and noise-induced hearing loss. Scand Audiol 30:236–244
Verbeek JH, van Dijk FJ, de Vries FF (1987) Non-auditory effects of noise in industry. IV. A field study on industrial noise and blood pressure. Int Arch Occup Environ Health 59:51–54
Wald N, Howard S, Smith PG, et al (1973) Association between atherosclerotic diseases and carboxyhaemoglobin levels in tobacco smokers. Br Med J 1:761–765
Weiss W (1970) How smoking affects hearing. Med Times 98:84–88
Wilson RW (1967) Data from the National Health Survey: cigarette smoking and health characteristics, July 1964–June 1965. Vital Health Stat 10. National Center for Health Statistics, Hyattsville
Wu TN, Chiang HC, Huang JT et al (1993) Comparison of blood pressure in deaf-mute children and children with normal hearing: association between noise and blood pressure. Int Arch Occup Environ Health 65:119–123
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This research was supported by Grant-in-Aid for Scientific Research (B)16790347 on Hearing Research on individual lifestyles and artheriosclerotic mechanism from Japanese Ministry of Education, Science, Sports and Culture. We thank Dr. Tetsurou Okino and Mrs. Eiko Ono of the Mitsubishi Materials Corporation and Mr. Hiromi Jinushizono and Mr. Kaname Suwa of the Saitama Health Promotion Corporation for their valuable help.
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Nomura, K., Nakao, M. & Yano, E. Hearing loss associated with smoking and occupational noise exposure in a Japanese metal working company. Int Arch Occup Environ Health 78, 178–184 (2005). https://doi.org/10.1007/s00420-005-0604-z
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DOI: https://doi.org/10.1007/s00420-005-0604-z