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Actin acting at the Golgi

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Abstract

The organization, assembly and remodeling of the actin cytoskeleton provide force and tracks for a variety of (endo)membrane-associated events such as membrane trafficking. This review illustrates in different cellular models how actin and many of its numerous binding and regulatory proteins (actin and co-workers) participate in the structural organization of the Golgi apparatus and in trafficking-associated processes such as sorting, biogenesis and motion of Golgi-derived transport carriers.

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Acknowledgments

G.E. thanks current and past members of his laboratory for their support, good work and stimulating discussions, and many friends and colleagues for suggestions, criticisms and/or reagents that altogether have contributed to the progress in our research in this field. G.E. also thanks Darya Gorbenko, Rosa M. Ríos and Bruno Goud for critical reading of the manuscript, and Robin Rycroft for his invaluable editorial assistance. Carla Serra, Enric Gutiérrez and Laia Salcedo-Sicilia are recipients of predoctoral fellowships from the Spanish or Catalonian Science agencies. The work carried out in our laboratory has been regularly supported by grants from Spanish government.

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  1. Departament de Biologia Cel·lular, Immunologia i Neurociències, Facultat de Medicina, Universitat de Barcelona, C/Casanova, 143, 08036, Barcelona, Spain

    Gustavo Egea, Carla Serra-Peinado, Laia Salcedo-Sicilia & Enric Gutiérrez-Martínez

  2. Institut d’Investigació Biomèdica August Pi i Sunyer (IDIBAPS) i de Nanociencia i Nanotecnologia (IN²UB), Universitat de Barcelona, 08036, Barcelona, Spain

    Gustavo Egea

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  1. Gustavo Egea
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Egea, G., Serra-Peinado, C., Salcedo-Sicilia, L. et al. Actin acting at the Golgi. Histochem Cell Biol 140, 347–360 (2013). https://doi.org/10.1007/s00418-013-1115-8

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