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Assessment of epiretinal membrane formation using en face optical coherence tomography after rhegmatogenous retinal detachment repair

  • Retinal Disorders
  • Published:
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Abstract

Purpose

To investigate epiretinal membrane (ERM) formation using en face optical coherence tomography (OCT) after vitrectomy for rhegmatogenous retinal detachment (RRD).

Methods

We retrospectively reviewed the medical records of 64 consecutive eyes (64 patients) with RRD treated by vitrectomy without ERM and internal limiting membrane peeling. ERMs and retinal folds were detected by B-scan and en face imaging. The maximum depth of retinal folds (MDRF) was quantified using en face imaging. ERM severity was staged using B-scan imaging. Main outcome measures were ERM detection rate with B-scan and en face imaging, MDRF, ERM staging, postoperative best-corrected visual acuity (BCVA; logarithm of the minimum angle of resolution), and risk factors for ERM formation.

Results

The detection rate for ERM formation was significantly higher with en face imaging (70.3%) than with B-scan imaging (46.9%; P = 0.007). There was no significant difference in postoperative BCVA between eyes with ERM formation (0.06 ± 0.26) and those without ERM formation (0.01 ± 0.14; P = 0.298). Forty of 45 (88.9%) eyes with ERM formation were classified as stage 1. Twenty-seven of 45 (60.0%) eyes with ERM formation developed parafoveal retinal folds. The mean MDRF was 27.4 ± 32.2 μm. Multiple retinal breaks and a maximum retinal break size of ≥ 2 disc diameters were significantly associated with ERM formation (P = 0.033 and P = 0.031, respectively).

Conclusion

Although ERM formation was observed in 70.3% patients after RRD repair, the formed ERM was not severe and had minimal impact on the postoperative visual acuity.

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Data availability

Data are available on request.

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Authors and Affiliations

  1. Department of Ophthalmology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1, Shikata-cho, Okayama, 700-8558, Japan

    Ryo Matoba, Yuki Kanzaki, Shinichiro Doi, Sayumi Kanzaki, Shuhei Kimura, Mio Morizane Hosokawa, Yusuke Shiode, Kosuke Takahashi & Yuki Morizane

Authors
  1. Ryo Matoba
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  2. Yuki Kanzaki
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  3. Shinichiro Doi
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  4. Sayumi Kanzaki
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  5. Shuhei Kimura
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  6. Mio Morizane Hosokawa
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  7. Yusuke Shiode
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  8. Kosuke Takahashi
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  9. Yuki Morizane
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Contributions

Conceptualization: Ryo Matoba; formal analysis and investigation: Ryo Matoba, Yuki Kanzaki, Shinichiro Doi, Sayumi Kanzaki; data curation: Shuhei Kimura, Mio Morizane Hosokawa, Yusuke Shiode, Kosuke Takahashi; writing–original draft: Ryo Matoba; supervision: Yuki Morizane.

Corresponding author

Correspondence to Yuki Morizane.

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All investigative procedures were conducted in accordance with the tenets of the Declaration of Helsinki, and the study was approved by the Ethics Committee of Okayama University Hospital, Okayama, Japan.

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Informed consent was obtained from all individual participants included in the study.

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The authors declare no competing interests.

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Matoba, R., Kanzaki, Y., Doi, S. et al. Assessment of epiretinal membrane formation using en face optical coherence tomography after rhegmatogenous retinal detachment repair. Graefes Arch Clin Exp Ophthalmol 259, 2503–2512 (2021). https://doi.org/10.1007/s00417-021-05118-y

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