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Sensitivity and specificity of monochromatic photography of the ocular fundus in differentiating optic nerve head drusen and optic disc oedema

Optic disc drusen and oedema

  • Neurophthalmology
  • Published:
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Abstract

Background

Evaluation of the efficacy of monochromatic photography of the ocular fundus in differentiating optic nerve head drusen (ONHD) and optic disc oedema (ODE).

Methods

Sixty-six patients with ONHD, 31 patients with ODE and 70 healthy subjects were studied. Colour and monochromatic fundus photography with different filters (green, red and autofluorescence) were performed. The results were analysed blindly by two observers. The sensitivity, specificity and interobserver agreement (k) of each test were assessed.

Results

Colour photography offers 65.5 % sensitivity and 100 % specificity for the diagnosis of ONHD. Monochromatic photography improves sensitivity and specificity and provides similar results: green filter (71.20 % sensitivity, 96.70 % specificity), red filter (80.30 % sensitivity, 96.80 % specificity), and autofluorescence technique (87.8 % sensitivity, 100 % specificity). The interobserver agreement was good with all techniques used: autofluorescence (k = 0.957), green filter (k = 0.897), red filter (k = 0.818) and colour (k = 0.809).

Conclusions

Monochromatic fundus photography permits ONHD and ODE to be differentiated, with good sensitivity and very high specificity. The best results were obtained with autofluorescence and red filter study.

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Authors and Affiliations

  1. Ophthalmology Unit, Alcorcon Foundation University Hospital, Madrid, Spain

    Pablo Gili, Patricia Flores-Rodríguez, Julio Yangüela & Javier Orduña-Azcona

  2. Health Sciences Faculty, European University of Madrid, Madrid, Spain

    Pablo Gili

  3. Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile

    Patricia Flores-Rodríguez

  4. Preventative Medicine Unit, Rey Juan Carlos Hospital, Madrid, Spain

    María Dolores Martín-Ríos

  5. Unidad de Oftalmología, Hospital Universitario Fundación Alcorcón, C/ Budapest 1, 28922 Alcorcón, Madrid, Spain

    Pablo Gili

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  1. Pablo Gili
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  2. Patricia Flores-Rodríguez
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  3. Julio Yangüela
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  4. Javier Orduña-Azcona
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  5. María Dolores Martín-Ríos
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Correspondence to Pablo Gili.

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Gili, P., Flores-Rodríguez, P., Yangüela, J. et al. Sensitivity and specificity of monochromatic photography of the ocular fundus in differentiating optic nerve head drusen and optic disc oedema. Graefes Arch Clin Exp Ophthalmol 251, 923–928 (2013). https://doi.org/10.1007/s00417-012-2223-1

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  • DOI: https://doi.org/10.1007/s00417-012-2223-1

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