Skip to main content

Advertisement

Log in

Pattern of myopia progression in Chinese medical students: a two-year follow-up study

  • Medical Ophthalmology
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Objective

To estimate myopia progression during a 2-year period in a cohort of medical students in mainland China.

Methods

A 2-year longitudinal study was performed among 2,053 Chinese medical students (mean age 18.27 years, 1,057 females and 996 males) with their refraction measured at the start and the end of this study by autorefraction in cycloplegia. Information about the students’ age, gender, home origin (urban or rural), and eye history was obtained through a questionnaire.

Results

The overall prevalence of myopia increased significantly from 78.5 % to 84.1 % (P < 0.001, right eye) and the mean refractive error increased significantly from −2.52 ± 2.13 D to −2.84 ± 2.16 D (P < 0.001, right eye) over the 2 years. The rural students had a significantly greater increase in prevalence of myopia and the refractive error towards myopia than the urban ones (P < 0.01 and 0.001 respectively). Females had a significantly faster myopic shift than males (P < 0.001). Participants with myopia initially showed the fastest myopic shift among the initial refractive groups. The relationship between the initial refractive error and the myopic shift remained significant after adjusting for sex and home origin (P < 0.05).

Conclusions

Myopia progressed as increase in prevalence of myopia and change in refraction towards myopia in this study population. Participants who were more myopic at baseline were more likely to have myopia progression. Female and rural participants had a faster myopic shift compared to male and urban ones, respectively.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Fledelius HC (2000) Myopia profile in Copenhagen medical students 1996–1998. Refractive stability over a century is suggested. Acta Ophthalmol Scand 78:501–505

    Article  PubMed  CAS  Google Scholar 

  2. Midelfart A, Aamo B, SjØhang KA, Dysthe BE (1992) Myopia among medical students in Norway. Acta Ophthalmol (Copenh) 70(3):317–322

    Article  CAS  Google Scholar 

  3. Woo WW, Lim KA, Yang H, Lim XY, Liew F, Lee YS, Saw SM (2004) Refractive errors in medical students in Singapore. Singap Med J 45:470–474

    CAS  Google Scholar 

  4. Lin LLK, Shih YF, Lee YC, Hung PT, Hou PK (1996) Changes in ocular refraction and its components among medical students. A 5-year longitudinal study. Optom Vis Sci 73:495–498

    Article  PubMed  CAS  Google Scholar 

  5. Erismann F, Curtin BJ (1985) The myopias: basic science and clinical management. Harper & Row, Philiadelphia

    Google Scholar 

  6. Goss DA, Winkler RL (1983) Progression of myopia in youth: age of cessation. Am J Optom Physiol Opt 60:651–658

    Article  PubMed  CAS  Google Scholar 

  7. Goldschmidt E (1968) On the etiology of myopia: an epidemiologic study. Acta Ophthalmol(Suppl) (Kbh) 98:1–172

    Google Scholar 

  8. Jacobsen N, Jensen H, Goldschmidt E (2008) Does the level of physical activity in university students influence development and progression of myopia? — a 2-year prospective cohort study. Invest Ophthalmol Vis Sci 49:1322–1327

    Article  PubMed  Google Scholar 

  9. Wu HM, Seet B, Yap EP, Saw SM, Lim TH, Chia KS (2001) Does education explain ethnic differences in myopia prevalence? A population-based study of young adult males in Singapore. Optom Vis Sci 78(4):234–239

    Article  PubMed  CAS  Google Scholar 

  10. Edwards MH, Lam CYS (2004) The epidemiology of myopia in Hong Kong. Ann Acad Med Singap 33:34–38

    PubMed  CAS  Google Scholar 

  11. Cohen J (1988) Statistical power analysis for the behavioral sciences, 2nd edn. Academic Press, New York

    Google Scholar 

  12. Fesharaki H, Kamali B, Karbasi M, Fasihi M (2006) Development of myopia in medical school. Asian J Ophthalmol 8:199–202

    Google Scholar 

  13. Chow YC, Dhillon B, Chew PT, Chew SJ (1990) Refractive errors in Singapore medical students. Singap Med J 31:472–473

    CAS  Google Scholar 

  14. Adams DW, McBrien NA (1992) Prevalence of myopia and myopic progression in a population of clinical microscopists. Optom Vis Sci 69:467–473

    Article  PubMed  CAS  Google Scholar 

  15. Onal S, Toker E, Akingol Z, Arslan G, Ertan S, Turan C, Kaplan O (2007) Refractive errors of medical students in Turkey: one year follow-up of refraction and biometry. Optom Vis Sci 84:175–180

    Article  PubMed  Google Scholar 

  16. Saw SM, Katz J, Schein OD, Chew SJ, Chan TK (1996) Epidemiology of myopia. Epidemiol Rev 18:175–187

    Article  PubMed  CAS  Google Scholar 

  17. Lu B, Congdon N, Liu X, Choi K, Lam DS, Zhang M, Zheng M, Zhou Z, Li L, Liu X, Sharma A, Song Y (2009) Associations between near work, outdoor activity, and myopia among adolescent students in rural China. Arch Ophthalmol 127(6):769–775

    Article  PubMed  Google Scholar 

  18. Shulkin DJ, Bari MM (1986) Deteriorating vision: an occupational risk for the medical student. Arch Ophthalmol 104:1274

    Article  PubMed  CAS  Google Scholar 

  19. Kinge B, Midelfart A (1999) Refractive changes among Norwegian university students — a three-year longitudinal study. Acta Ophthalmol Scand 77:302–305

    Article  PubMed  CAS  Google Scholar 

  20. McBrien NA, Adams DW (1997) A longitudinal investigation of adult-onset and adult-progression of myopia in an occupational group. Invest Ophthalmol Vis Sci 38:321–333

    PubMed  CAS  Google Scholar 

  21. Bullimore MA, Reuter KS, Jones LA, Mitchell GL, Zoz J, Rah MJ (2006) The study of progression of adult nearsightedness (SPAN): design and baseline characteristics. Optom Vis Sci 83:594–604

    Article  PubMed  Google Scholar 

  22. O’Neal MR, Connon TR (1987) Refractive error change at the United States Air Force Academy — class of 1985. Am J Optom Physiol Opt 64:344–354

    Article  PubMed  Google Scholar 

  23. Ellingsen KL, Nizam A, Ellingsen BA, Lynn MJ (1997) Age-related refractive shifts in simple myopia. J Refract Surg 13:223–228

    PubMed  CAS  Google Scholar 

  24. Krause U, Krause K, Rantakallio P (1982) Sex differences in refraction errors up to age of 15. Acta Ophthalmol 60:917–926

    CAS  Google Scholar 

  25. Xu L, Li J, Cui T, Hu A, Fan G, Zhang R, Yang H, Sun B, Jonas JB (2005) Refractive error in urban and rural adult Chinese in Beijing. Ophthalmology 112:1676–1683

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We thank the students for their participation and the ophthalmologists and the officers of Teaching Administration at Weifang Medical University for their contribution to this study.

This study was supported by grants from Shandong Provincial Education Department (S07WZ73) and Weifang Medical University, PR China.

Conflict of interest

None of the authors have any proprietary interests or conflicts of interest related to this submission.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zhenghou Zhang.

Additional information

This submission has not been published anywhere previously, and it is not simultaneously being considered for any other publication.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lv, L., Zhang, Z. Pattern of myopia progression in Chinese medical students: a two-year follow-up study. Graefes Arch Clin Exp Ophthalmol 251, 163–168 (2013). https://doi.org/10.1007/s00417-012-2074-9

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00417-012-2074-9

Keywords

Navigation